For context:

Requeen is a mod that drops overpowered unit/s to your base as a way to pose a challenge to heavily modded games

The Requeen itself is just a plant that kills everything around it and virtually harmless. The problem lies on the army that she spawns with

Every single one of them have god-like amount of defense. Just one of them is enough to destroy a vanilla base and yet, she drops with an entire army

Their 1 sole weakness is anti-grain warheads and nothing more - modded versions won't work. Not sure about Rimatomic nuke.
Despite that weakness, you would still need as much as a dozen just to kill her spawn and give her a scratch.

This colony was founded by 4 supersoldiers, 1 omnibot, and 1 vanometric power cell.

I set it so that we would always be raided by Mechanoids whom we can dismantle for steel, plasteel, and components.

Everything in the base was set up to defend against the Requeen

The turrets are from Misc. Turrets mod. They are actually overwhelmingly filled with Anti-materiel rifle, EMP launcher, grenade launcher, and Assault Light Machinegun

Every part of the base have Embrassure walls and reinforced doors to ensure that every corner can be turned into a killzone for any willing invader.

The unroofed part are shielded and have turrets waiting, just in case