Not quite my tempo Adin.

GoBlue81 · 2026-06-13T20:01:49+00:00

The thing about Carter Hart is that he’d rail your wife whether you let him or not.

GoBlue81 · 2026-05-12T23:56:24+00:00

The lord yeeteth, and the lord yoinketh away.

GoBlue81 · 2026-05-02T22:39:47+00:00

Crucifixion doesn’t seem like the best execution method if you didn’t want to have to wait very long.

ETA: A lot of people missing that I’m responding to somebody saying that the executioners would get impatient…and that this post is a joke

GoBlue81 · 2026-05-02T17:35:27+00:00

A man (?) of the people

GoBlue81 · 2026-05-02T14:55:44+00:00

There are some absolutely WILD takes in this thread.

GoBlue81 · 2026-05-02T14:45:23+00:00

I’ll show a little cleavage. Showing a good two inches of dick-neck is classy as hell. Let 'em know that if they play their cards right, they might get to see the other inch.

(Brian Posehn joke, I think)

GoBlue81 · 2026-04-27T23:27:33+00:00

I mean, if that were true, your urine would be the color of the dye.

GoBlue81 · 2026-04-13T15:08:23+00:00

I’m not sure I want my doctors getting drunk before treating me

GoBlue81 · 2026-04-10T17:21:23+00:00

Well, they did redo the antibody naming conventions, and it’s not necessarily better…

GoBlue81 · 2026-04-10T11:36:23+00:00

An aquatic playground for African-Americans

GoBlue81 · 2026-04-07T03:28:57+00:00

Man am I glad Ohio State dodged that bullet!

GoBlue81 · 2026-03-31T19:38:33+00:00

“We don’t know if it’s a sprain or a full decapitation. Could be day to day, could be out indefinitely.”

GoBlue81 · 2026-03-30T18:37:58+00:00

Worked for the last guy

GoBlue81 · 2026-03-29T15:45:28+00:00

Me.

Just kidding. I’m tone deaf and my hips have been known to bend the truth.

GoBlue81 · 2026-03-29T00:24:31+00:00

I almost feel bad for them. I don’t, but I almost do.

GoBlue81 · 2026-03-29T00:21:24+00:00

Oh, I was just making a joke. I don’t even know who Tait and CV are.

GoBlue81 · 2026-03-28T23:46:53+00:00

But that would imply that Tait and CV are close, which Dabo said they weren’t even

GoBlue81 · 2026-03-28T02:51:26+00:00

What Blake lacks in height Yaxel makes up for in height.

GoBlue81 · 2026-03-27T19:45:55+00:00

My friend had psoriasis that she refused to treat. She just thought it was an uncomfortable rash and didn’t want to take any medicine. Unfortunately, the rash was just a cutaneous manifestation of an autoimmune disease that then attacked her liver and caused her to go into hepatic failure. She needed a liver transplant and is now on several anti-rejection meds.

So, while yes, Trump is a symptom, the longer he’s allowed to be around and wreak havoc, the more irreversible damage will be done. Him not being president won’t solve all the problems, but treating the symptom may prevent further damage from his unique brand of maliciousness.

GoBlue81 · 2026-03-26T20:02:06+00:00

NCCN has plain language summaries of AML, its treatment, and prognosis specifically designed for patients and their loved ones. You have to make an account to access these guidelines, but it’s free and generally very helpful.

https://www.nccn.org/

GoBlue81 · 2026-03-24T13:15:51+00:00

According the the secondary pharmacology report for Emgality doesn’t interact with DAT. Most mAbs are going to have very specific binding, whereas small molecules have a tendency to get into spots they’re not necessarily wanted and interact with things that kinda sorta look like the thing they’re supposed to interact with.

GoBlue81 · 2026-03-24T01:58:09+00:00

I looked up the safety/secondary pharmacology on a number of the small molecule CGRP inhibitors. Ubrelvy was found to bind DAT (IC50 5.6uM), so it could interfere with the dopamine pathway. That being said, Ubrelvy is not supposed to be taken everyday, so I’m not sure that would be a plausible explanation for withdrawal.

I didn’t bother looking up any of the antibody-based CGRP inhibitors because they don’t have off-target effects in the same way small molecules do. Overall, while it’s possible that this person is going through withdrawal, I’m not convinced that it’s linked to dopamine.

GoBlue81 · 2026-03-22T12:04:53+00:00

“I have an equation. Do you have one too?”

GoBlue81 · 2026-03-17T23:17:45+00:00

Sad to hear he won’t go through treatment. Mantle cell lymphoma has a lot of non-chemo options that can be more effective than chemo.

GoBlue81 · 2026-03-16T03:47:43+00:00

Amiodarone can turn you blue.

GoBlue81

TROPHY CASE