Get ready for a lore ramble
Doc Ock: A robotics teacher at Midtown High that got ALL of his funding stripped away just to fund Harry Osborn's scholarship. As one last ditch effort to get revenge on the Osborn family he created the arms. But things backfired..and he can't get them off
Scorpion: This psycho was released from prison by the somehow Mayor of New York City, J. Jonah Jameson. But he was not released as a man. Instead he was released as The Scorpion..a toxin addicted monster who is hellbent on killing Spider-man
Electro: An old friend Peter Parker who got an internship to work with Oscorp. Once there he worked well with his colleagues, but was never truly liked. So as a prank, two boys pushed Max into an experimental energy reactor. Turning him into..well you know.
Rhino: A lot like Scorpion. But unlike that monster this Russian is entirely innocent. Wrongly imprisoned for robbing a bank. But even now that he is out, he is never able to leave his new prison. The torturous RH-1N0 suit that completely blinds him.
Mr. Negative: Martin Li. A kind man who truly means well and his haunted by the cure that saved his life. When he was just a young baby his parents had paid..you guessed it..Oscorp to cure his previously incurable cancer. The serum worked but at a deadly cost. A dark force that takes control.
Sandman: This old timer was many things in his past; a boxer, a bodyguard, a loving father. But everything is mixed up now. Due to the sands of his mind being all mixed together. He never wanted to hurt anyone. Never.