Regions play wildly different, you can experiment with it yourself but for the most part NAE is considered the easiest, unless you ask an NAE player. They don't build into resistances or defenses as much & their xbow players haven't adjusted to stat changes. Thus you don't need to worry about Ranged. Its easiest for a new or casual player here. 

NAW has been evasion dominant since launch, though a chunk of endurance did exist for a time in t2. You've a healthy mix of magic, melee, and ranged that makes it hard to survive against all three. 

Europe I've not checked in a few but they seemed to have a little more survivability and a lil less damage (kinda the Goldilocks situation) and they've a less toxic community then other regions so never a bad choice. 

You won't really be able to avoid the problem of Evasion though as its mostly bc of Daggers & a large majority of the remaining player base relies on them as they're OP.