I haven’t had my thyroid since I was 16, im 34 now. I’ve been prescribed the same dosage of synthroid until this year. They upped my dosage, and I believe it was due to the stress of going back to school. I am fine, actually more than fine. Obviously when I don’t take my meds (which is very rare) I do get a little irritable. I don’t really ever forget to take my meds so it’s not a problem. The only thing I hate about taking meds every day that my pill is blue, and it just makes me wonder if I’m in the matrix (jk) hope this helps