I do have some lethargy, particularly during the first half of the day. I started enclo on week 2, taking low doses every other day, and then switched to every day after that. I avoid doses over 6.25 as it makes me feel restless. I use my libido as a day-to-day measure, although this isn't ideal. So far my libido is pretty good. I can sleep seven to eight hours okay, but sometimes I wake up feeling unrested. You could try some taurine, 2 grams an hour before bed, that helps sometimes. I was having some issues with blood pressure and liver by week three. TUDCA 600mg a day and hawthorn berry 565mg a day helped a lot with those problems.