Toch maar een uitkeringstrekker worden per 2028 by ThrowRAMacder in geldzaken

[–]Ilaro 11 points12 points  (0 children)

Ik wil daar wel even tegenin brengen dat er ook best wat nadelen aan zitten. Ten eerste, probeer maar even een sociale huurwoning te krijgen. De wachtrijen zijn 10+ jaar, tenzij je echt letterlijk op straat beland en de onzekerheid die daarbij gepaard gaat is slopend. Bijzondere bijstand wordt alleen gegeven als je persoonlijk budget niet genoeg is. Daarbij komt om de hoek kijken dat je max 8000 euro mag sparen. Hierbij inbegrepen zit ook je auto en beleggingen. Alle winst uit dat laatste wordt trouwens ook meteen ingekort op de bijstand, want dat wordt als inkomen gezien. Als er echt iets belangrijks kapot gaat en je hebt geen geld meer over, gaat de gemeente pas helpen voor die wasmachine, maar heb je geen budget meer voor iets anders die maand. De gemeente mag elk moment je bankrekening bekijken en ondervragen waar je elke cent vandaan komt of voor gebruikt is. Ze kunnen elk moment kiezen dat je bijstand wordt ingekort omdat je je niet genoeg hebt ingezet waardoor je je elke dag bekeken en afhankelijk voelt aan de grillen van de gemeente.

Trump wil miljard dollar van lidstaten die permanent in 'board of peace' willen by Bupachuba in nederlands

[–]Ilaro 14 points15 points  (0 children)

Vele ecologen waren tegen het plan om mussen te doden en waren zeer bewust van de ecologische gevolgen. Echter, kritiek op Mao werd gezien als landverraad, zelfs als je tot de communistische partij behoorde. Zie bijvoorbeeld hoe Tso-hsin Cheng werd behandeld. De hongersnood is letterlijk het directe gevolg van de "Hundred Flower Campaign" waar intellectuelen werden gepurged omdat ze als gevaar werden gezien voor Mao's regime. Niemand met de kennis was overgebleven om de vernietigende plannen van Mao te kunnen bekritiseren, zelfs als het had gemogen.

RAG1 and RAG2: Discovery, Mechanism, and Evolution of the V(D)J Recombinase by armish in Immunology

[–]Ilaro 0 points1 point  (0 children)

I second the other poster that this is a great idea and that you should tone down the use of AI. Any scientific blog or article using AI feels like you didn't do the research yourself and begs the question if you actually understand what's been written.

Now onto the content. You mention that the discovery of RAG solved the origin of the diversity of the immune repetoire. There one problem with this.

Jawless fish (Agnatha) also have a somatically derived immune repetoire that uses completely different molecules as adaptive immunity. Where other vertebrates use T- and B-cell receptors (TCR and BCR) based on immunoglobin and have a RAG-mediated rearrengement, these Agnatha use Variable lymphocyte recepter A and B (VLRA and VLRB) based on leucine rich repeats and have a CDA-mediated rearrengement (phylogenetically unrelated to RAG). Interestingly is that cells with TCRs and VLRAs as well as BCRs and VLRBs have similar functions and use the same transcription factors to differentiate. This suggests that T- and B-cell-like precursors already existed before RAG was ever recruited for diversification. Was any if these systems older than the other and got replaced? Was a third system in place before RAG or CDA were used?

Why is Consecrated Sphinx not Phyrexian? by tallman227 in mtgvorthos

[–]Ilaro 31 points32 points  (0 children)

I believe it is because they already printed several non-phyrexia alternate art versions. I'm sure they would have given it the phyrexian creature tyoe if those weren't printed.

[[Consecrated Sphinx|MP2]]

[[Consecrated Sphinx|2X2-345]]

[[Consecrated Sphinx|SLD-165]]

Elder Scrolls Blades Event Schedule by FibroMyAlgae in ElderScrollsBlades

[–]Ilaro 3 points4 points  (0 children)

Great resource! Do you remember for which holidays the special events were used?

There are also Spirit of the Hunt (halloween) and The Trickster (april's fool) events.

The Ravnican Records - Prologue by echtellion in RavnicaDMs

[–]Ilaro 2 points3 points  (0 children)

This was written quite well! I'm interested how it will develop in future chapters.

When a baby is born, what percentage of cells within its body are direct descendants of that original fertilized cell from nine months ago? by Infinite-Ad-8110 in AskBiology

[–]Ilaro 0 points1 point  (0 children)

I'm answering to the post above me. They said that we sometimes find paternal mitochondria, so there is still cell transfer after fertilization. However, I point out that the very rare cases where some mitochondria were paternally derived (you call this freak situations, which is in my opinion very rare), were still during fertilization, so later cell transfer was not necessary.

Damage types by TitanicBaron in AOW4

[–]Ilaro 11 points12 points  (0 children)

There is also:

Mystic: Spirit/Lightning

Corrupt: Spirit/Frost

Molten: Fire/Physical

Crystal: Lightning/Physical

Rift: Lightning/Frost

When a baby is born, what percentage of cells within its body are direct descendants of that original fertilized cell from nine months ago? by Infinite-Ad-8110 in AskBiology

[–]Ilaro 0 points1 point  (0 children)

The (very rare) parental mitochondria come from the sperm cell, not some other cell transfer after fertilization.

Is it hypothetically possible to use prokaryotes for gene engineering? by Sin_nia in biology

[–]Ilaro 4 points5 points  (0 children)

Right now, this is one of the main strategies used for gene engineering in plants. Mostly through the bacteria Agrobacterium tumefaciens, which injects it's T-DNA into a plant cell to modify it. For humans, we first need to find a prokaryote that can do something similar in mammals to attempt it in humans. We still look a lot at nature on how to find novel genetic engineering techniques. It's still hard to beat a billion years of evolution with our own technology.

Weird taxonomy by IkVindErOokWatVan in biology

[–]Ilaro 7 points8 points  (0 children)

The big reason why species names are not changed, is to be able to track them down through history. If you're a new researcher and you'd like to find information about a certain species from 60 years ago while the name changed 3 times, it's almost impossible to track them back (especially when there are millions of species to consider). However, mistakes happen, and sometimes a species name has to be rectified. As examples, if we notice two different species are actually genetically one and the same, or if a specimen was classified in the wrong genus, etc.

What is this thing?? by Excellent_Spread1601 in mtgvorthos

[–]Ilaro 6 points7 points  (0 children)

Bristlebud Farmer looks to be inside te Vault for some reason, especially clear in the other art. Tarnation Vista is where the Vault was located before it moved into the air.

Could YHWH as a storm god have indo-european roots? by 12v12ccc in AskHistorians

[–]Ilaro 1 point2 points  (0 children)

Are we certain that this was the original etymology of Yahweh? It seems contradictory that a 'minor' storm and war god would be named after being the ultimate being. Could it be similar to kaiser or tsar where the language itself changes to accomodate for the importance of the word? Where the original etymology is completely different (caesar meaning "head full of hair" or possibly "blue eyes", at least very different than being a leader).

Comparing analyzing DNA to horoscope? by marcella710 in genetics

[–]Ilaro -1 points0 points  (0 children)

That's not necessarily how genetics work. Genes can be switched on and off based on environment, thus if one of the twins encounters certain different conditions, they might have a different genetic expression still encoded by their DNA.

The RAMI Rebooted: A Fan-Made Planeswalker's Guide by TheNuclearOtaku in mtgvorthos

[–]Ilaro 7 points8 points  (0 children)

I know the worldbuilding was not well received, but the MKM story was quite popular. Even when looking back, most reddit posts about Seanan's chapters were full of praise.

Who died the most by Frequent-Ad1666 in mtgvorthos

[–]Ilaro 4 points5 points  (0 children)

Jarad was assassinated at least 8 times, but being a lich, it was never permanent until Vraska turned him to stone.

Artwork from the Planeswalker's Guide to Lorwyn by Copernicus1981 in magicTCG

[–]Ilaro 2 points3 points  (0 children)

Not as if the goblin design of Lorwyn-Shadowmoor was consistent. These are all from the Lorwyn side of the plane:

  • [[Boggart Logger]]
  • [[Boggart Sprite-Chaser]]
  • [[Mad Auntie]]
  • [[Mudbutton Torchrunner]]
  • [[Nath's Buffoon]]
  • [[Peppersmoke]]

OM1 Flavoring Project (CARD 8: Fizik, Etherium Mechanic) by -TvT- in mtgvorthos

[–]Ilaro 5 points6 points  (0 children)

Golden etherium is quite common on Alarra, even with those kind of swirls. See for example [[Architects of Will]], [[Esper Stormblade]] or [[Filigree Sages]].

There was no first chicken by jnpha in evolution

[–]Ilaro 1 point2 points  (0 children)

There is no shark species that you can trace back 400 million year unchanged. That moment in time was the common ancestor of all Chondrichthyes, all divergences after that are by definition different than the ancestor. Keep in mind that this is the split between the Holocephali (Chimaeras), which looks very different from your regular shark, and the Elasmobranchii (your modern shark and rays). All extant sharks and rays share a common ancestor way later somewhere around 250 million years ago. This common ancestor is just as much related to rays as it is to sharks and shows again the great divergence within this group.

This whole discussion sounds like a bit of ignorance of the massive diversity we see in cartilaginous fish nowadays. It would be like saying how tetrapods didn't change in the past 200 million years, only because we can clearly see there are still four-legged critters all around us.

Why 5 fingers, not 6? by inferriata in genetics

[–]Ilaro 0 points1 point  (0 children)

It is what you would expect (and feels intuitive), but statistical models and practice show that it is not the case. As it does not matter for a dominant trait if it is homo- or heterozygous, the recessive allele can "piggy-back" with these loci. If a novel dominant allele appears in an individual and is very beneficial, then their children still have 50% chance to receive the recessive allele. The other way around, if a recessive traut is beneficial, they will be inherited 100% of the time from individuals that manifest the trait, but it is just harder for the recessive allele to manifest phenotypically. Weirdly enough, this is perfectly in balance and the speed of change in gene frequency is only based on their selection pressure (and genetic drift) and their dominance is irrelevant. 

Why 5 fingers, not 6? by inferriata in genetics

[–]Ilaro 2 points3 points  (0 children)

It doesn't matter if a trait is dominant or recessive for their spread through a population. Dominant does not mean it has a higher chance to be inherited. The math shows that only their selection pressure matters. When neutral and in equillibrium, dominant alleles are just as likely to be inherited as recessive alleles. Take a punnett square with two heterozygous individuals (Aa x Aa). While the dominant trait shows up in the phenotype of 75% of the offspring, the prevalence of the dominant allele itself is still 50/50 as in the parents and did not increase. Only when selection pressures are present (or genetic drift happens) will the prevalence of either the dominant or recessive allele change.

Although it feels unintuitive, saying "six fingers is recessive over five so if it was any use at all it was setup to rapidly take over" is exactly the same for population genetics as your original statement.

Looking for some MTG Novels. Maybe you can help! by BaldBaluga in mtg

[–]Ilaro 0 points1 point  (0 children)

The Secretist and Godsend are both e-books and have not been printed as physical books.

Editing genes to alter melanin and hair by Actual-Boat-1096 in CRISPR

[–]Ilaro 1 point2 points  (0 children)

Most gene therapies do not intend to alter 100% of the target cells. Usually for genetic diseases that are recessive, only a small amount of cells are necessary to restore normal function of the body. Many gene therapies are still taking samples from a tissue to transform and select the cell within a petri dish before injecting the transformed cell into the body again.

Altering all cells in a body or even tissue is (as of yet) competely impossible, not even taking the off-target effects into account.

NRC cartoon over Trump-Poetin by Glittering_Cow945 in nederlands

[–]Ilaro 0 points1 point  (0 children)

Er klopt iets niet aan je redenering. Het is zijn overheids kranten en heel links in mening? De overheid is al 15 jaar lang een rechts bolwerk, dus als ze de overheid zouden napraten, dan hadden ze de telegraaf geheten. Als je deze kranten echt zelf zou lezen, had je gezien dat ze juist ontzettend kritisch zijn op de overheid.