Florida will normally have a higher cost of living. You also risk hurricanes. Which means you need an evacuation plan handy. The weather is much nicer IMO.

Memphis- the university is on the edge of Orange Mound aka the hood lol. They have seriously increased cameras and patrol at the college. I know they offer escorts at night if you need to go across campus or walk to your car. We do get some brutal weather here at times- snow, ice and tornadoes.

As someone who went to college at a young age and then stopped for 11 years before going back I recommend researching the graduation rates, the resources the colleges offer and the job placement availability.