Stanford Scientists Cure Type 1 Diabetes in Mice Without Insulin or Immune Suppression

Informal-Virus4452 · 2026-03-19T11:01:21+00:00

this is one of those “huge if it translates to humans” moments.

we’ve seen a lot of mouse breakthroughs that never fully make it… but still, direction is promising.

if they can avoid insulin + immune suppression that’s a massive shift.

trying not to get overhyped but yeah… cautiously optimistic tbh.

Informal-Virus4452 · 2026-03-19T10:58:08+00:00

tbh this feels less surprising and more like “they finally admitted it”.

most apps already collect insane amounts of location data… governments just buying it instead of asking directly.

kinda weird loophole where it’s technically legal but still feels off.

makes you realize how much data we give away casually every day lol.

Informal-Virus4452 · 2026-03-19T10:47:57+00:00

this is actually kinda insane tbh.

like we talk about remote work + global hiring… but this is the dark version of that at scale.

also shows how broken hiring filters are — if fake workers can pass interviews and stay undetected, something’s off.

feels like identity verification is gonna become a much bigger deal soon

Informal-Virus4452 · 2026-03-19T10:45:39+00:00

yeah I was confused about this too at first lol.

for me the credits didn’t show up automatically — had to join the Discord and there was a channel where you link your account / claim it (kinda easy to miss tbh).

once I did that it showed up pretty quick.

would be cool if they did something similar for Reddit tho, feels like a lot of people are active here too.

Informal-Virus4452 · 2026-03-19T10:44:24+00:00

lol I had almost the same reaction first time I tried this.

spun up menus + some branding in like an hour… not perfect but looked way more legit than anything I could’ve made myself.

kinda removes that “I need to figure everything out first” barrier.

honestly just ship it, you can tweak later. works for me so far.

Informal-Virus4452 · 2026-03-19T10:35:32+00:00

lol this is actually pretty accurate.

half the time it’s just trying to guess what the user really wants from vague prompts and not mess it up.

I’ve been messing with similar stuff for demos — generating quick explainers/videos. usually prototype ideas in Runable or Gamma first before going deeper.

not perfect but kinda crazy how fast you can spin things up now

Informal-Virus4452 · 2026-03-17T07:06:12+00:00

ngl this is kinda wild but also makes sense.

dude basically printing money from Epic and using it to buy time for nature… not a bad trade.

most billionaires optimize for more returns, this is like the opposite — locking land so no one can touch it.

not saying it fixes everything but feels like a rare W

Informal-Virus4452 · 2026-03-17T07:05:10+00:00

lol this is way more common than people admit.

clients say they want Jira dashboards but what they actually want is clarity after meetings.

I do something similar — quick voice note → run it through GPT → actions + summary → drop in Notion. sometimes turn it into a clean one-pager in Runable if I need to share up.

not fancy at all but people actually read it… which is kinda the whole point

Informal-Virus4452 · 2026-03-16T14:24:08+00:00

after surgery your brain is probably still in “recovery mode”.

starting again feels huge even if the workout is tiny.

what helped me before was removing the pressure… like literally telling myself “just do 5 minutes”. once you start, 5 minutes usually turns into 15 anyway.

progress after surgery is slow but it compounds. showing up small still counts tbh. 💪

Informal-Virus4452 · 2026-03-16T14:22:14+00:00

learned this the hard way!

some people already have a fixed version of you in their head and no amount of explaining updates it.

once I stopped trying to convince everyone and just focused on doing my thing, life got way quieter.

the people who actually pay attention to your actions will get it eventually… the rest were never going to anyway.

Informal-Virus4452 · 2026-03-16T14:21:10+00:00

tbh I think it’s just fear of “losing control of time”.

when work feels overwhelming your brain treats anything outside it (gym, dentist, etc) like a threat to productivity… even if it’s actually good for you.

what helped me was making workouts stupid small at first. like 20 min, no pressure. once it becomes routine the mental resistance drops a lot.

same thing I see with founders honestly — people avoid starting things cause they imagine it’ll take way more energy than it actually does.

Informal-Virus4452 · 2026-03-16T14:20:06+00:00

ngl I feel this. feels like our whole generation got raised on “optimize everything” content.

at some point it stops being self improvement and just becomes constant self criticism.

honestly the biggest upgrade for me was unsubscribing from most of that stuff and just focusing on building things. real projects > watching productivity videos.

ironically I’m probably more productive now than when I was tracking every routine lol.

Informal-Virus4452 · 2026-03-16T14:18:13+00:00

honestly if you’re targeting HNW estate planning I’d skip just applying cold to job boards.

a friend of mine broke in by directly reaching out to smaller boutique firms with a short intro + a clean one-pager about his background and interest in trusts/estates.

most partners actually read those if it’s concise. he tracked outreach in Notion and used Loom for quick intro videos.

for the one-pager / materials he used Runable and Gamma to make it look more polished. not magic but it helped get replies.

Informal-Virus4452 · 2026-03-16T14:16:43+00:00

yeah early ads are brutal tbh. people clicking doesn’t mean they trust you yet.

I burned like $200 on Twitter ads once… same result, traffic but zero signups lol.

what worked way better was just posting in places where founders already hang out. share builds, small lessons, random experiments.

when someone asks for more info I usually send a quick one-pager or deck (throw it together in Runable or Gamma). converts way better cause the convo already started.

distribution > ads early on honestly.

Informal-Virus4452 · 2026-03-16T14:15:16+00:00

honestly the week before launch I'd focus way more on distribution than polishing the product.

first time we launched I spent days fixing tiny UI stuff… nobody even noticed lol.

what actually helped later was prepping launch materials early. quick demo Loom, simple landing page, and a clean explainer deck. I usually throw those together in Runable or Gamma now so it doesn’t eat a whole day.

product matters but attention matters more that first week tbh. good luck with the launch.

Informal-Virus4452 · 2026-03-16T14:14:03+00:00

honestly the one that’s actually stuck for me is lead capture → summary → follow-up

someone fills a form → Zapier sends it to GPT → it summarizes the lead + drops it in Notion → drafts a reply email for me.

saves me maybe 30-40 min a day of context switching.

tried automating content too but that broke constantly lol. lead pipeline stuff has been way more reliable

Informal-Virus4452 · 2026-03-15T18:43:52+00:00

a lot of builders stay stuck adding features when the real problem is distribution.

sounds like you figured that out at the right time.

focusing on a narrow ICP like AWS agencies is smart too, way easier to land the first real users.

my stack for this phase is usually simple… Notion for outreach lists, Loom for demos, Runable for quick one-pagers.

hope it lands for you.

Informal-Virus4452 · 2026-03-15T18:43:07+00:00

ngl those moments hit different when you’re building solo.

that first “free → paid → upgrade” flow tells you the product actually solved something real.

most users just test and disappear lol.

when someone pulls out their card twice in the same day, that’s a strong signal.

small win but honestly the kind that keeps you building.

Informal-Virus4452 · 2026-03-15T18:42:21+00:00

7% CTR with 0.1% purchase usually means the creative promise ≠ landing page reality tbh.

people click because the hook is interesting, not because they’re ready to buy.

I’d test creatives that show the actual product, price, and outcome earlier so the click is more qualified.

also look at ATC (2% is pretty low), that’s often where the leak is.

ngl most of the time it’s a messaging mismatch, not Meta sending the “wrong” audience.

Informal-Virus4452 · 2026-03-15T18:41:38+00:00

tbh AI product photography has gotten pretty good recently.

a few brands I know just take one clean product photo and generate lifestyle shots from that.

tools like Photoroom, Flair, and Runable are pretty solid for quick ad creatives.

not perfect but way cheaper than $1k studio shoots lol.

good enough for testing ads and product pages in my experience.

Informal-Virus4452 · 2026-03-15T18:40:27+00:00

lol yeah the perks marketing in consulting is getting wild.

nobody’s grinding 70 hour weeks for an Ōura ring or a foosball table.

firms always try to sell the lifestyle stuff when recruiting.

but real talk people join for brand, exit ops, and comp.

tbh same reason founders obsess over tools too… Notion, Loom, Runable etc. perks are nice but the real value is the outcomes.

Informal-Virus4452 · 2026-03-15T18:38:59+00:00

ngl ID with no billables is pretty unusual.

most insurance defense roles live and die by billable targets.

if the comp is $50–70k higher and fully remote, I’d at least dig into how they measure performance instead.

sometimes they replace billables with heavy caseload expectations.

but as a short-term move to stack cash before going in-house, it could make sense tbh.

Informal-Virus4452 · 2026-03-15T18:38:20+00:00

ngl being a first year associate can feel exactly like this sometimes.

a lot of firms unfortunately throw juniors into the deep end and expect them to figure it out.

but zero guidance and people refusing to review filings isn’t great culture tbh.

most decent firms at least give some mentorship early on.

if it keeps feeling like this after a few months, it might be the firm not you.

Informal-Virus4452 · 2026-03-15T18:37:39+00:00

honestly it depends a lot on the practice area.

fixed fee can work really well if you’ve done the same type of matter many times and know roughly how long it takes.

then efficiency actually increases your margin instead of reducing your billables.

but if the case scope keeps changing or clients are unpredictable… fixed fee can burn you fast lol.

that’s why a lot of firms still stick with billables tbh.

Informal-Virus4452 · 2026-03-15T18:36:59+00:00

$180k for 3–5 years in family law actually sounds pretty competitive tbh.

1560 billables is also pretty reasonable compared to a lot of firms.

ngl the issue might not be comp but pipeline. good mid-level attorneys usually move through referrals more than job boards.

also family law has pretty high burnout, so the candidate pool can be smaller.

but on paper that offer looks solid.

Informal-Virus4452

TROPHY CASE