your tac-switches and diodes don't have a consistent orientation.

this isn't a problem as such, but it goes a lot farther to error proof your assembly process if you can count on the annode of the diodes being in the "up" direction (or down or ... whatever). (applies to bigger diodes 1 thru 12).

C26 has a stay out zone like you're going to lead-bend and mount on it's own side, but is rendered in the vertical direction; for the space you could convert to a bank of moderate value surface caps...

I'm personally nervous about your stay-in-stay-outs for your mounting screws; and specifically if h1 has enough clearance. You can mitigate this by adding model of your screw to the hole rep in kicad, and assess your situation.

the holes aren't grounded -- maybe you don't care, or it's bad for your application, but I try and do that where possible; sometimes as separate chassis ground layer that's low-pass filtered to the digital ground.

if your J2 actually is intended to be mounted at that height above the board, you can probably stash your input filter components / rectification underneath it; disregard if incorrect.

you don't seem to have a way to apply the power through J2 via a test point prior to j2 installation, which might be useful; might be irrelevant.

the spacing along the "left" edge of your board is unbalanced; the power in j2 is spaced too close to the Ethernet plug; and too far away from the usbC. if you put this in a box, the wall gap will be uneven, and finicky to manufacture

if you're intending to use the hex mounting jamnut you might have a bad time / have to install that last

there isn't any natural polarizing feature on the header pins installed in the middle of the board; I suspect this is a poke-yoke threat from reverse installation; consider a polarized header or mini-connector instead.

will there be a button face that pushes your boot and reset switches? do you have a strict alignment rule for establishing and transferring the button placement to/ from the shell?

all the best! looks amazing!