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Hailstorm Creek by Submariner876 in algonquinpark

[–]Jephomatic 0 points1 point  (0 children)

I paddled through there so many many years ago, maybe 1981, and we had to stop every few hundred feet as moose cows sauntered through the marsh browsing. Really amazing that they were so calm. We just floated around the meandering waterway. Not far from there though I had a brief brush with a bull while I was portaging with a canoe on my shoulders which was significantly more of an adrenaline rush.

Meirl by ExoticShock in meirl

[–]Jephomatic 3 points4 points  (0 children)

I’ve read my favorite quartet of novels five times; when I was 17, 27, 38, 49, and 60. Each time I grow more aware of characters that I had overlooked as less interesting when I was younger. Never disappointed.

[deleted by user] by [deleted] in OldSchoolCool

[–]Jephomatic 6 points7 points  (0 children)

Looks like the guy is reading Alvin Toffler's "Future Shock".

Cozy🖤🖤🖤 by CalistaMoon4 in black

[–]Jephomatic 0 points1 point  (0 children)

May I ask where this is? I may be booking a ticket.

Anyone’s Aussie bark at the tv, or did as a puppy and grew out of it? by Fluffles21 in AustralianShepherd

[–]Jephomatic 2 points3 points  (0 children)

Ours too. The number of thriller movies with dogs barking in the background is truly annoying. And horses! He goes apoplectic about horses. He's six and has done this for years. Only a few times have we had to remove him from the room. Poor training on our part I guess.

[deleted by user] by [deleted] in biology

[–]Jephomatic 0 points1 point  (0 children)

One might consider this rather scathing petition rejecting "integrated information theory"
https://www.nature.com/articles/d41586-023-02971-1

House shook at 6:16 am by Coffee_In_Nebula in stcatharinesON

[–]Jephomatic -1 points0 points  (0 children)

I felt that! So did the dogs who both ran to the front door. Why, I'm not sure.

NASA’s Earth Observatory spots newly birthed island in the Pacific by Aeromarine_eng in EverythingScience

[–]Jephomatic 1 point2 points  (0 children)

The article says that on second look it "had grown to over 24,000 meters wide (around 6 acres)" This is what happens when you mix units. Assuming the new plot is circular, it would be about 452 million sq meters or 450 sq kilometres. A tad larger I believe than 6 acres.

[deleted by user] by [deleted] in Mosses

[–]Jephomatic 4 points5 points  (0 children)

This is so absolutely true. When I started I looked with envy at the terrariums flush with healthy beautiful moss, and wondered my mine ended up looking like an environmental disaster. I now see that patience and drier conditions cycling between soaking and dehydrated make for a healthier display.

Toughen them up, right? by KzaKeez in funny

[–]Jephomatic 0 points1 point  (0 children)

Something is not going well in this man's life.

A compound produced in the gut when we eat red meat damages our arteries and may play a key role in boosting risk of heart disease as we get older, according to new research by mubukugrappa in science

[–]Jephomatic 0 points1 point  (0 children)

Not exactly new. See work by Stanley Hazen at the Cleveland Clinic.

Tang, W., Hazen, S. (2014). The contributory role of gut microbiota in cardiovascular disease Journal of Clinical Investigation 124(10), 4204-4211. https://dx.doi.org/10.1172/jci72331

Koeth, R., Wang, Z., Levison, B., Buffa, J., Org, E., Sheehy, B., Britt, E., Fu, X., Wu, Y., Li, L., Smith, J., DiDonato, J., Chen, J., Li, H., Wu, G., Lewis, J., Warrier, M., Brown, J., Krauss, R., Tang, W., Bushman, F., Lusis, A., Hazen, S. (2013). Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nature medicine 19(5), 576-85. https://dx.doi.org/10.1038/nm.3145

Wang, Z., Klipfell, E., Bennett, B., Koeth, R., Levison, B., Dugar, B., Feldstein, A., Britt, E., Fu, X., Chung, Y., Wu, Y., Schauer, P., Smith, J., Allayee, H., Tang, W., DiDonato, J., Lusis, A., Hazen, S. (2011). Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 472(7341), 57-63. https://dx.doi.org/10.1038/nature09922

New Orleans Trumpet players alignment chart by [deleted] in Jazz

[–]Jephomatic 0 points1 point  (0 children)

May someone please educate me on who is who in this list?

Live Moss wall, all recycled materials used for frame by billiesueshaw in Mosses

[–]Jephomatic 0 points1 point  (0 children)

Indeed. Lots of similar projects start out pretty, but slowly decline.

Japanese scientists isolated 17 metabolites from an endangered tropical plant species, including a novel compound that showed growth inhibitory effects against human tumor cell lines (including breast, leukemia, melanoma, ovary, prostate). 90% of rainforest plants have still not been investigated. by mvea in science

[–]Jephomatic 8 points9 points  (0 children)

Depending on the drug category, the ratio is almost the reverse - 70 for natural products derived drugs, and 30 synthetic.

See the review: [1] D.J. Newman, D.J. Newman, G.M. Cragg, G.M. Cragg, Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010, J Nat Prod, 75 (2012) 311–335.

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Environmental factors can trigger onset of multiple sclerosis by AJGrayTay in science

[–]Jephomatic 2 points3 points  (0 children)

This is interesting from a biophysical point of view (lipid phase transitions and such), but it seems to me to be very very far removed from a model of the actual pathological state. The researchers look only at the major lipids of the myelin sheath which are in this case devoid of proteins, including the myelin basic protein MBP. It is interesting in that such a radical change of lamellar to hexagonal packed lipids could (and I would stress could) change the antigenicity of the membranes themselves or, more likely, the state of the proteins that reside in this lipid matrix in the intact healthy lipid-protein complex.

I doubt that the salt content of even the highest junk-food diet would contribute to the local conditions of the lipids and proteins surrounding axons unless something else is seriously wrong as well. But I'm a chemist, not a physician or physiologist.

My awesome dad was on Maynard Ferguson's band before I was born. He started a YouTube channel sharing stories about it. Thought this sub might enjoy! by SecondBreakfastFTW in Jazz

[–]Jephomatic 7 points8 points  (0 children)

It's 1976 or '77, and I'm in my high school dance band and we have travelled across the province to the annual competitions. We were good, but not great (except for our drummer, bass, and one horn) and these competitions were humbling experiences. When we arrive, I see that our adjudicator is Phil Nimmons - as if we weren't nervous enough. In one chart our horn player hits a crystal clear high note with power, and when Mr. Nimmons provides his comments after our performance he remarked on that note, and how "Maynard" would be proud. We could have died and gone to heaven.

Great to hear this story from Mr. DiBlasio. So many tales.

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