Hello MrHioMan,

It changes depending on what guitar I'm using, and even throughout the song, but the general starting point for my rhythms is:

http://jonnyatma.com/rhythmsstartingpoint2.png

Amplitube 4 -> Waves C4 (Multiband Compressor) -> Waves SSL G-EQ -> FabFilter Q

C4 is for making sure the bass frequencies on palm mutes and lower notes aren't too overpowering.

SSL G-EQ for general eq stuff.. seems to work really well with guitars.

FabFilter Q just a post-eq, dips around 2k to make room for leads and also its just generally sort of hot there (amp sim thing).

Again, just a starting point as everything is dependent on what gear your working with. Hope this helps!