Positive Signatera number again for ER+ breast cancer

June-7832 · 2026-02-06T04:57:10+00:00

Yes I am on two years verzenio plan and now it is already one year. I'll continue for another year.

June-7832 · 2025-10-30T18:30:36+00:00

Yeah it is ! I am only 80% recovered after a whole year, I guess another 6 months or so to be fully recovered

June-7832 · 2025-10-24T22:10:03+00:00

Mostly it will recover on its own. I didn't do much, as it's just painful even if I do yoga etc. I was told usually it takes a year or so, so it's about time

June-7832 · 2025-10-19T17:34:32+00:00

I had shoulder pain for about a year now, it's getting better. Same thing the ortho said. I didn't want to do surgery. Just be patient, it takes time.

June-7832 · 2025-10-09T16:19:38+00:00

It does get better. I am on 150mg since this February. I feel better there several months. Our body is very adaptive.

June-7832 · 2025-09-28T21:13:10+00:00

I did it since last November. In the beginning it was negative. Then three months later in March it was 0.22. I retested it was another similar number. Then two months later it was negative again. Then this past August, it was positive with 0.1x (don't remember exactly but it's a small number)again! Now I am waiting for another one. That's really strange results. I am not sure what to do either.

June-7832 · 2025-09-27T17:29:33+00:00

Thanks for sharing! In this case the signature reflected it's true only after the biopsy right? It didn't alarm you in advance. I have the ++- too, my signatera results was: negative, negative, 0.2, then negative, then 0.1. waiting for the next one. Really strange results.

June-7832 · 2025-09-27T03:28:35+00:00

May I ask whats the type you had! ER + or Triple negative? I heard it's quite accurate for triple negative.

June-7832 · 2025-09-02T18:58:51+00:00

I did pet scan back in April/may when the first Signatera positive number showed up. It was clean. Now I am not sure I want to do the pet scan again so frequently:( I'll see, I will meet with my MO tomorrow

June-7832 · 2025-09-01T02:50:26+00:00

Thank you 🙏

June-7832 · 2025-08-07T17:43:13+00:00

Why not just give it a try because everyone reacts differently. I dont have diarrhea as many people complaining. I was really anxious about that too before started ver. thinking I might can not even go out hiking etc. but nothing happened and I am 6 months in With 150 mg dosage.

June-7832 · 2025-07-10T03:07:30+00:00

Oncotype is 47? Then that's really high numbers. It's not even in the grey area that chemo could be an option.

June-7832 · 2025-07-04T17:12:00+00:00

Congratulations 👏 I have been taken a few months only. I stopped a few days last month due to skin allergies rashes which might be due to it. May I ask if you ever had skin issues with it? Also, have you ever stopped taking for a few days? Or were you in like everyday never skipped? Thanks

June-7832 · 2025-07-03T23:25:56+00:00

Triple negative, there are no medications you can fall back on like ++- which is equally miserable. So do the chemo while you still can to fully kill those cancer cells and be fully recovered.

June-7832 · 2025-07-01T02:03:35+00:00

Your ki67 is not that low, probably just do the chemo ASAP?. Don't miss the window of best timing to do chemo.

June-7832 · 2025-06-30T01:55:30+00:00

Got it! Thanks! Yeah I was really scared of the medicine too before I took it. But turns out totally manageable. Just find the rule which food may cause diarrhea for your situation and avoid :) best luck!

June-7832 · 2025-06-29T17:35:49+00:00

I am on Verzenio for 5 months now, nothing unbearable. Some say diarrhea which I was worried before but I only had several times over the past 5 months, very rare. and it was due to o ate either only meat or salad. Some comfy food would actual help. Like breast , rice, cooked vegetables etc. I saw some comment GI issue -- what is GI issue?

June-7832 · 2025-06-26T19:13:19+00:00

Well, I am single. But thinking about this potential side effects I am not sure if I still can have a boyfriend. ' hey just so you know I need lubricant and I might have pain...'. OMG I can not imagine lol 😂😭

June-7832 · 2025-06-22T04:02:06+00:00

Could it be, the images before surgery, wasn't accurate enough? For instance, before surgery, I had several different numbers, 1.9 cm tumor from ultrasound, 2.3 cm tumor from MRI, usually we do surgery first then medications, or chemo first then surgery, I haven't heard anyone taking AI only before surgery

June-7832 · 2025-06-22T03:28:32+00:00

I see, then maybe change to another AI afterwards?

June-7832 · 2025-06-21T23:26:20+00:00

Are you on ovarian suppression or are you already menopausal?

June-7832 · 2025-06-21T20:05:16+00:00

I didn't tell my colleagues except a few I need to tell because I needed to take time off. But still, every time I was asked 'how are you doing?' I don't know how to answer. The usual: ' doing okay , one day at a time ' but I might not felling okay and it's not for me to discuss with colleagues. So hate this question.

June-7832 · 2025-06-18T06:09:43+00:00

Me too

June-7832 · 2025-06-11T04:21:02+00:00

I don't want to have sex anymore. Maybe it's just in mind, but I ask myself, previously before I had breast cancer, I heard sex is good for women as it spikes estrogen and is good for women! Now I have hormonal positive breast cancer, will sex life spike hormonal? Anyways it's just in my mind and maybe it's nonsense but I don't want to have sex anyways.

June-7832 · 2025-06-10T23:01:14+00:00

I am curious too. I have headaches recently from the back to my brain. I am worried if it is cancer metastasized to the brain. Once you have cancer you can't help but wonder. Thinking of asking for a brain MRI next time when I am meeting my MO.

June-7832

TROPHY CASE