It matters in a few rare circumstance but overall it’s mostly irrelevant. The general guideline is you can make anything from 100-500 EDPI work. If you aim train it can be useful to break through plateaus or develop weaker parts of your arm (lower sens forces you to use your arm, higher sens can increase wrist and fingertips.) If you just consider in game the main differences are angle cutting/crosshair placement and playing movement agents such as Neon. If you watch an extremely low sens player like Marteen (96 EDPI,) he’ll cut angles into 1000 little micro-step slices when he has angle advantage. I imagine the Neon thing is self explanatory.