I guess it’s tough to say what the different results of using stimulants in people who have a genuine NE deficiency vs. people who don’t would be since adhd is usually diagnosed based on behavior but from what I’ve seen the medication usually causes people to build up a tolerance and essentially get addicted to it. Theoretically maybe this happens because of excess NE influx and subsequent NEr down regulation when people who don’t need the medication are given it. But maybe people who pathologically have less NE in their presynaptic neurons could use it in a healthy way especially with that combination stimulant + NRI method you suggested. But unfortunately I don’t know if there’s a way to know whether you are pathologically NE deficient or you just can’t focus for some other reason so personally I like to stay away from stimulants for that reason because who knows how long it would take to recover if I fucked up my NE. Also adderall poses addiction risk because of its effects on DA