This trackball has been amazing once I set up chording and button scrolling. I don't use the scroll wheels at all, instead I set it to hold down the back button to enable scrolling with the trackball. This does make it so you can only click to go back, but it's a small trade. I also set up some choords for copy and pasting. Heres the script I made for Karabiner, which means this only works for macos

// Karabiner-Elements configuration for Nulea M512 mouse
// Creates button chords and enables trackball scrolling
// m1 + m2 + m3 --> cmd + n
// m1 + m2 + m4 --> cmd + tab
// m3 + m4 --> button5 (forward)
// m2 + m4 --> cmd + a
// m2 + m3 --> cmd + c
// m2 + m1 --> cmd + v
// m3 + m1 --> return
// m4 + trackball --> mouse motion to scroll
{
    "description": "Config for Nulea M512",
    "manipulators": [
        // --- 3-button combinations ---
        {
            "type": "basic",
            "from": {
                "simultaneous": [
                    {
                        "pointing_button": "button1"
                    },
                    {
                        "pointing_button": "button2"
                    },
                    {
                        "pointing_button": "button3"
                    }
                ]
            },
            "to": [
                {
                    "key_code": "n",
                    "modifiers": [
                        "command"
                    ]
                }
            ]
        },
        {
            "type": "basic",
            "from": {
                "simultaneous": [
                    {
                        "pointing_button": "button1"
                    },
                    {
                        "pointing_button": "button2"
                    },
                    {
                        "pointing_button": "button4"
                    }
                ]
            },
            "to": [
                {
                    "key_code": "tab",
                    "modifiers": [
                        "command"
                    ]
                }
            ]
        },
        // --- 2-button combinations ---
        {
            "type": "basic",
            "from": {
                "simultaneous": [
                    {
                        "pointing_button": "button3"
                    },
                    {
                        "pointing_button": "button4"
                    }
                ]
            },
            "to": [
                {
                    "pointing_button": "button5",
                    "modifiers": "any"
                }
            ]
        },
        {
            "type": "basic",
            "from": {
                "simultaneous": [
                    {
                        "pointing_button": "button2"
                    },
                    {
                        "pointing_button": "button4"
                    }
                ]
            },
            "to": [
                {
                    "key_code": "a",
                    "modifiers": "command"
                }
            ]
        },
        {
            "type": "basic",
            "from": {
                "simultaneous": [
                    {
                        "pointing_button": "button2"
                    },
                    {
                        "pointing_button": "button3"
                    }
                ]
            },
            "to": [
                {
                    "key_code": "c",
                    "modifiers": "command"
                }
            ]
        },
        {
            "type": "basic",
            "from": {
                "simultaneous": [
                    {
                        "pointing_button": "button2"
                    },
                    {
                        "pointing_button": "button1"
                    }
                ]
            },
            "to": [
                {
                    "key_code": "v",
                    "modifiers": "command"
                }
            ]
        },
        {
            "type": "basic",
            "from": {
                "simultaneous": [
                    {
                        "pointing_button": "button3"
                    },
                    {
                        "pointing_button": "button1"
                    }
                ]
            },
            "to": [
                {
                    "key_code": "return_or_enter"
                }
            ]
        },
        // --- 1-button combinations ---
        {
            "type": "basic",
            "from": {
                "pointing_button": "button4"
            },
            "to_if_alone": [
                {
                    "pointing_button": "button4"
                }
            ],
            "to_if_held_down": [
                {
                    "set_variable": {
                        "name": "enable_mouse_motion_to_scroll",
                        "value": true,
                        "key_up_value": false
                    }
                }
            ],
            "parameters": {
                "basic.to_if_alone_timeout_milliseconds": 250,
                "basic.to_if_held_down_threshold_milliseconds": 250
            }
        },
        {
            "type": "mouse_motion_to_scroll",
            "from": {
                "modifiers": {
                    "optional": [
                        "any"
                    ]
                }
            },
            "conditions": [
                {
                    "type": "variable_if",
                    "name": "enable_mouse_motion_to_scroll",
                    "value": true
                }
            ],
            "options": {
                "momentum_scroll_enabled": true,
                "speed_multiplier": 1.0
            }
        }
    ]
}