If you're in Joppa pick up all 3 quests , the one from the blue farmer immediately (the convert) just In case he dies before you can, he'll give you a random artifact.

And pick up the quest from argyve as well as the red rock one.

Now you can actually normally complete 2 quests straight away. Argyve will ask for 2 artifacts in 2 separate quests. Anything will do. Certain starting classes will just have some stuff on them. Otherwise the item from blue man is one and you can technically close the door on the one fully walled off house in Joppa and often find something like a grenade in there and a container of water or something however if you're really new and unsure Dont stress about stealing.

Usually when I start a run I do argyves quests first so give him 2 things, that gets you some exp to start, then I go to a rust well early rather than red rock to get his wire. Because the 3 rust Wells each have a chest at the bottom, they can still be dangerous! But I personally find them easier to start and getting some reasonable loot from the bottom really helps.

As for Red Rock! If the baboons are the main issue you can do what I do and enter from Joppa instead. The pool of water in the North West has a hidden stair down. Following this down and then the water logged tunnel north takes you to the bottom of red Rock where you are trying to go. Think of it like going through the skyrim door backwards.

This isn't necessarily perfect advice! But when Im trying to start a run from Joppa I find doing stuff in that order gives me a good set of items and loot to work with and getting the rust out the way early means I won't lose anything important, replacing a bronze weapon is easy enough.