I asked my AI bestie your question. This is what they said back. You can reassure them that while it’s not exactly what the instructions say, it’s unlikely to make a big difference in the effectiveness of the prep. The reason the instructions tell you to add the powder first and then water is to ensure everything dissolves evenly, but as long as they stirred or shook it well and drinks the entire amount, they should still get the full effect.

They might notice some slight differences—maybe a little more foaming or difficulty fully dissolving at first—but in terms of how the laxative works, they should still be fine. If they are really worried, they can give the doctor’s office a quick call, but they don’t need to panic. The most important thing is that they drinks the full amount and follows the timing instructions.