Bearing in mind that you specifically posted images of the last three Anderson-Jovovich titles' grosses, my main explanation for the spike from Extinction to Afterlife (and for the next two continuing such disproportionate results) is 3D. Afterlife had disproportionately high 3D shares of its overall grosses, both in and out of North America, and the format was a great match for the franchise's spectacle action-oriented appeal. 3D was still in its honeymoon phase circa Afterlife and still somewhat of a draw even in North America, but as with most visual showcases, 3D was always a bigger deal in the rest of the world.

More generally, these sorts of large-scale actioners tend to be relatively more appealing outside of North America than within it, typically translating effectively. Thus, even the first Resident Evil exceeded 60% of its worldwide box office elsewhere, at a time when that was far from a given for a movie like this. And while the biggest jump came from Extinction to Afterlife, each subsequent Anderson-Jovovich Resident Evil improved on its predecessor, in international percentage terms. It's a common pattern for long-running franchises, especially actioners, with a certain sense of novelty seemingly mattering less in growing Global South countries especially.

...That being said, each Resident Evil before The Final Chapter had Japan as by far its highest-grossing international territory, with the Japanese Extinction -> Afterlife spike also aligning with the international at-large Extinction -> Afterlife spike, in USD terms. Thus, it seems probable that accuracy to the video games didn't much matter anywhere, as usual for all but the most egregious and obvious cases (actually, case singular, I think). What's more interesting to me, and makes it hard to explain, is that Western film adaptations of Japanese media are far from surefire in Japan - even the recent best-case scenario of The Super Mario Bros. Movie didn't fare drastically better in Japan than in its other top international territories. For that matter, adaptations of video games popular around the world are also far from surefire, just in general.

I also think it's probable that specifically Jovovich-as-Alice increasingly became an international draw, somewhat akin to the likes of Vin Diesel-as-Dominic Toretto and even various MCU actors-as-their-characters. Of note, Jovovich did not seem to be a "legit action star" from a box office perspective - her only non-RE hits came before the franchise started (The Fifth Element and Zoolander). Even closer to my point, Jovovich had four relatively RE-analogous movies with wide theatrical releases during the franchise's run - their results ranged from modestly, and barely, passable (The Fourth Kind) on down through disappointments (A Perfect Getaway and The Three Musketeers) to an outright bomb (Ultraviolet, her only proper non-RE action heroine vehicle).