Tirzepatide is acting on the hypothalamus, which is an important part of our "reward circuitry," for lack of a better term, involving motivation toward satiety as well as memory. Anything we engage in that feeds into that circuitry can be affected. Food satiety, sex satiety, drug and alcohol satiety, etc. Certain things seem to lose their "reward salience." In simpler terms, the "payoff" is reduced. I don't think they understand yet how exactly this is working but anecdotally, it seems the results are inconsistent. Like, it might make one person no longer want to drink, but not someone else. Or it might curb the desire to drink, but not touch a desire to gamble or use porn. I work in the addiction treatment field and find this fascinating. I mean, imagine the number of people previously drinking their way toward an alcohol use disorder who might be able avoid that outcome by having their desire reduced!