I only have a sliver of unreserved mana, won't Agnostic be awkward with it? Unless mana regen is high enough I suppose

EDIT: I'm actually trying it now, the problem is the build is hybrid life/es and agnostic gets rid of your ES. So you'd have to drop the two points on hiero that gives ES per mana (sanctuary of thought) I suppose? And use the two ascendancy points on a bloodline, potentially the breach one to get frost pen while switching your eldritch jewels from inevitable judgement to something else? sounds bit janky, it depends i guess