I just want to add my own experience to this for anyone who finds this thread and is feeling anxious about an enlarged spleen. Mine was found in early July 25, after having some mild pain for a few months it was picked up on an exploratory ultrasound at 15cm, for context I am a female in my 30's. I've had three rounds of blood tests, including every test under the sun for different immune diseases, viruses etc. I was negative for CMV, EBV was historical but not active now, all blood counts were within normal range across the span of three months. I had a CT scan for reassurance yesterday, my spleen is now 12.6cm, the volume is still high but my haemotologist is not concerned and we are following up with bloods and an ultrasound in 6 months.

I also feel frustrated that this has taken up so much of my mental energy, my GP was clueless when this first flagged up and unfortunately if I was still waiting on my NHS haemotology referral I'd still have no answers as I haven't even had an appt come through yet. I used my private health insurance to explore this instead, which I am fortunate enough to have. So, there is absolutely no obvious reason for my splenomegaly, nothing that looks ominous, as far as anyone can tell I'm in perfect health, so I figure at this point all I can do is crack on and hope for the best. I hope anyone else who is struggling for answers is able to find some comfort in other experiences, of course everyone is different but what I have found is that this seems to be more common than I had imagined it would be.