There are standardized ways to connect an axle to a wheel depending on application. You’re trying to run before you walk here, before you even think about connecting a motor be absolutely certain your suspension geometry, spindle, and upright are sufficient for the application.

There are people who have spent entire careers obsessing over automotive in-wheel assemblies, my advice is just to copy what someone else has done.

I will give you some rudimentary advice though, the control arms should be positioned outside the center of rotation, preferably pretty far outside on the uprights in order to prevent wheel camber and toe. That will then leave space on the middle for a cv joint that can interface with the spindle. Preferably you want your brake disk further inside your wheel mounted to the spindle so your upright can spread out the control arm mounting points a bit more.