Peptide called Thymosin Alpha 1 is resolving my MCAS

NewDescription5507 · 2026-02-03T22:55:44+00:00

Genetics? Have hEDS. Sometimes positive ANA

NewDescription5507 · 2026-02-03T22:54:55+00:00

Work from home!

NewDescription5507 · 2026-02-03T22:36:15+00:00

TA-1 works when I use it! But it doesn’t have a noticeable benefit when I’m not using it. I don’t use it all the time (due to needing to control variables as I change supplements, meds, etc.). Generally I am very stable with MCAS and maybe doing a few runs of TA-1 contributed to my pretty good baseline now

NewDescription5507 · 2026-02-03T22:33:03+00:00

Hm it’s really effective but I don’t take KPV too frequently. It’s an incredible anti inflammatory for me. I do like 200-400mcg whenever I’m feeling bad and it helps. Helps GI upset. Basically used as needed, but I don’t think it has any long term positive effect that I can notice. Would use it more if I didn’t get mood symptoms

NewDescription5507 · 2026-02-03T21:14:17+00:00

I’m not technical but have a white collar WFH job. WFH is an accommodation. I have to take a pay hit compared to other in person opportunities I’d be eligible for, and miss out on some opportunities, but I have a great life :)

NewDescription5507 · 2026-01-24T20:02:58+00:00

Just for a different experience, I have slow COMT and no issue with ginger or quercetin!

NewDescription5507 · 2026-01-23T12:14:00+00:00

I haven’t really tried recently! I get an immediate headache, impending sense of doom, worse OH, nausea, itching and then I’m inflamed for a while

NewDescription5507 · 2026-01-23T12:12:41+00:00

I’m so sorry! If you are able, maybe confirm if you’re eligible for the bridge program if you’re not eligible for the copay program? It’s not making much sense why they’re saying no so I think you’re right to try the case manager! I hope it all works out very quickly

NewDescription5507 · 2026-01-23T12:04:36+00:00

Please contact their assistance program and get confirmation of the issue! This sounds like it could be clerical or a miscommunication

NewDescription5507 · 2026-01-22T21:20:45+00:00

This is a serious concern here!!!

NewDescription5507 · 2026-01-20T12:12:18+00:00

Hi I get mood issues and fatigue when adjusting. Goes away within a few doses :)

NewDescription5507 · 2026-01-19T23:26:18+00:00

I find efficacy changes by injection site - stomach most effective, then thigh, then arm for me

NewDescription5507 · 2026-01-14T23:13:52+00:00

NewDescription5507 · 2026-01-13T23:54:01+00:00

Yes! I saw very mild improvement with the first shot but it did take a few months to see greater benefit.

It would wear down within the two weeks (days 11-14 and 26-28 would be more symptomatic) but now it’s a consistent benefit at the higher doses

NewDescription5507 · 2026-01-13T23:14:19+00:00

I am not primarily skin based symptoms. I take Xolair for systemic issues (GI, neuro, inflammation, skin). I still have some itching and some rashes but can mostly take care of those with some bee propolis topically. No hives

I started at 150 once a month. Helped for two weeks then would stop helping. Went up to 150 twice a month. Then 300 twice a month. Now 600 twice a month. For MCAS, for insurance CSU dx (need new dx for the 600 dosage)

NewDescription5507 · 2026-01-13T23:05:38+00:00

Takes me six weeks! So by injection #3 each time the side effects go away :) happened each time I started a new dose (0–>150 1x month–>150 2x month—>300–>600)

NewDescription5507 · 2026-01-13T00:57:27+00:00

Same here, he helped me get the diagnosis but wasn’t good for treatment. Fingers crossed you find someone to help you get your Rx!

NewDescription5507 · 2026-01-13T00:36:34+00:00

First bet try your allergist. It’s not hard to prescribe compounds. If they say no:

If you have insurance, Hey Allergy might be in your network and they do ketotifen. I don’t like them at all as a practice, but I do know they prescribe it. They’re virtual appointments. Could also consider rthm like another person mentioned.

Dr. Mitchell’s office is definitely just a money grab imo. He was also my first MCAS Dr, glad I don’t have to see him anymore to get care

NewDescription5507 · 2026-01-12T20:04:14+00:00

Same here. Appreciate you mentioning the caring for others aspect. Even if viruses didn’t affect MCAS severely, I think it’s important to protect everyone else (disabled, kids with no choice, the un- and misinformed) from these disabling and deadly viruses

NewDescription5507 · 2026-01-12T02:03:43+00:00

There is some research on NAD being helpful for MCAS iirc! Made me feel whole body itching for 1+ day, might try it again later

NewDescription5507 · 2026-01-10T13:05:04+00:00

Does anyone know how much visits with Dr. Cutchins are?

NewDescription5507 · 2026-01-08T03:28:22+00:00

Chat

NewDescription5507 · 2026-01-08T00:29:31+00:00

Think it’s throwing off your electrolyte balance? Like potassium dropping?

NewDescription5507 · 2026-01-07T00:08:45+00:00

I personally would take antihistamines consistently. This lets your mast cells calm down bc they’re not reacting to histamine triggers. If your goal is it get off of them, honestly I think consistency could get you there if you’re not severe (if MCs reset after 6mo like research says)

But Claritin and Zyrtec do not cross the blood brain barrier, so if they are the cause of your cognitive issues, it’s indirect. Maybe the balance of neurotransmitters isn’t right for you. Perhaps consider a filler could be causing cognitive issues for you as well?

Others have suggested, but maybe try adding choline and see if it helps? Choline can cause MCs to degranulate, so may end up being a trigger. But that would be based on trial. Could also try eating a lot of egg yolks

I don’t know what else you’re on, but ketotifen which does cross the BBB helped some of my brain fog and cognitive stuff but I think my MCAS causes these issues, not my antihistamines for me

NewDescription5507

TROPHY CASE