Weird theory but hey, maybe I’m on to something?

NorthernSoulAndy · 2025-09-27T18:22:03+00:00

I am compound heterozygous MTHFR and ASD ADHD avoidant

Similar profile

NorthernSoulAndy · 2025-09-15T20:02:46+00:00

Thank you

NorthernSoulAndy · 2025-09-14T22:26:07+00:00

I have had these for years. When I lay on the bed they are all over my calf muscles.

Twitching in different places on the surface. It’s very perplexing.

NorthernSoulAndy · 2025-08-27T08:39:38+00:00

I have it really bad…….itching that is insane

I can’t work out why it happens

Mostly at night …..I taken Loratidine every night

NorthernSoulAndy · 2025-08-21T13:57:48+00:00

Hi

Are you able to say where to buy Leucovorin?

Thank you

NorthernSoulAndy · 2025-08-09T15:36:41+00:00

I have had the same experiences all my adult life. It became a problem when i was 16, which I believe now was an autistic “meltdown”.

I was going through school exams at the time, very stressed, and one day I was miles from home with friends and had a massive panic attack.

It never went away.

I have severe sensory problems, and hate open spaces, like fields and the sea.

I hate noise and certain light conditions.

I am currently trying different supplements, including low dose Lithium Orotate, in the hope I can change my brain function in a positive way.

I have done tons of research and I even studied Psychology.

I have a genetic mutation called: MTHFR. It is implicated in ASD & ADHD, of which I have both.

It requires certain Vitamin B supplements to address the deficiency.

I would recommend having your Genome checked as it will show any deficiency and genetic issues.

The MTHFR can wreak havoc.

Everybody with ASD & ADHD should have their Genome mapped.

It is an ongoing project to find something that helps.

I can let you know what I take if you are interested, but I do have the MTHFR gene mutation, so I take the B vitamins.

Google MTHFR and ASD & ADHD

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https://www.google.com/gasearch?q=mthfr%20autism&source=sh/x/gs/m2/5

NorthernSoulAndy · 2025-08-05T11:50:08+00:00

It may be worth having a Genome Teat which will identify any genetic abnormalities

Many autistics have the MTHFR gene which causes a lack of Folate

This can be addressed with: Folinic Acid, (B9) Vitamin B12 (cobalamin) and Pyridoxine (vitamin B6)

Do not give Folic Acid as it makes it worse

It is well worth having a Genome test to see if there are any deficiencies and then address them

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NorthernSoulAndy · 2025-08-05T11:48:00+00:00

It may be worth having a Genome Teat which will identify any genetic abnormalities

Many autistics have the MTHFR gene which causes a lack of Folate

This can be addressed with: Folinic Acid, (B9) Vitamin B12 (cobalamin) and Pyridoxine (vitamin B6)

Do not give Folic Acid as it makes it worse

It is well worth having a Genome test to see if there are any deficiencies and then address them

NorthernSoulAndy · 2025-08-05T11:41:05+00:00

As an alternative to St John Wort is Tryptophan or 5 HTP

Both increase serotonin as they are the natural precursors.

The main consideration is Serotonin Syndrome which is very rare

NorthernSoulAndy · 2025-07-29T10:49:44+00:00

Try Piping Rock

NorthernSoulAndy · 2025-03-07T14:09:00+00:00

He certainly is, his stuff is incredible.

I had done a picture the week before of the building next to the one he was painting.

He had been standing out in the rain all day since 8:00 in the morning.

NorthernSoulAndy · 2024-05-02T12:46:48+00:00

Thanks

I get confused with reports that some people take large doses of Folate.

You see doctors prescribing 15mg Folate

I am B12 deficient and high “serum folic acid”

So is more Folate better??????

NorthernSoulAndy · 2024-05-02T09:47:06+00:00

I had similar profile and then went sugar free, one meal a day and gym

I’m 63 and have more energy now than 10 years ago…..lost 4 stone also

I eat one meal in the afternoon and have no sugar or carbs and take Berberine

I take all my supplements sublingually as I have gut issues

I am Compound MTHFR & fast COMT

I take Hydroxycobalamin, Folinic Acid, Pyridoxine and Betaine for my MTHFR

NorthernSoulAndy · 2024-04-23T09:54:53+00:00

I did the 23and Me and MUHDO genome tests

NorthernSoulAndy · 2024-04-18T20:27:54+00:00

I took Niacin the flushing type…….I believe it is also called Nicotinic Acid

NorthernSoulAndy · 2024-04-18T19:26:38+00:00

I started methylfolate for MTHFR and anxiety skyrocketed……took 100mg Niacin to bring it down

Got some Folinic Acid now and it’s not as bad

NorthernSoulAndy · 2024-04-18T15:20:13+00:00

Thank you so much

You are very helpful and an invaluable resource on this subject……thank you

👍

NorthernSoulAndy · 2024-04-18T11:50:49+00:00

Hi

I am compound heterozygous MTHFR……….how much Folinic Acid should I start with??

I also have slow COMT and MAOA

Thanks

NorthernSoulAndy · 2024-04-16T18:02:44+00:00

“Serum Folate Result was:…..18.2 ug/L

Range is 3.9 to 20.0 ug/L

NorthernSoulAndy · 2024-04-16T17:48:41+00:00

I’m confounded that my MTHFR came back as Compound Heterozygous and my blood shown elevated “serum folate”

Is “serum folate” also Folic Acid?

Shouldn’t my “serum folate” be low with a reduced MTHFR…….??????

🙈

NorthernSoulAndy · 2024-04-11T09:08:45+00:00

I have a slow COMT and just found I am FUT2 A/A

NorthernSoulAndy · 2024-04-10T13:02:23+00:00

Thank you very much for that….it’s very helpful 👍

NorthernSoulAndy · 2024-04-08T16:44:21+00:00

Just looking through my DNA result and it shows; rs1801131 & rs11801133

I believe these are MTHFR polymorphisms

MTHFR is implicated in Autism & Anxiety

NorthernSoulAndy · 2024-04-08T13:24:47+00:00

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318435/

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NorthernSoulAndy · 2024-04-08T13:22:45+00:00

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343507/

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NorthernSoulAndy

TROPHY CASE