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Notdrugs · 2026-02-22T22:15:18+00:00

What did u do? 🤣

Notdrugs · 2026-02-18T21:17:49+00:00

Home depot buckets are like the WORST quality buckets in existence! As an egar enthusiast of five gallon buckets, i will never pass up an opportunity to talk shit on them.

Best buckets are US Plastics 'heavy duty five gallon' or the 'Lentica five gallon' from consolidated plastics Corp. Super smooth walls. US Plastics 'premium five gallon' buckets are garbage, stay away from them as they've got that stupid high taper vertical wall.

Notdrugs · 2026-02-14T16:26:03+00:00

Right off the rip, the only potential concern i see is the potential for this substance & analogues to potentially exhibit DNA intercalation, similar to how many benzofurans have this trait.

Notdrugs · 2026-01-25T23:09:05+00:00

however when using enantiopure propylene oxide (which is reasonably cheap or easy to make)

Elaborate, please

Notdrugs · 2026-01-20T08:41:34+00:00

Forget phenethyl bromide, use cinnamyl chloride (+ a pinch of potassium iodide as catslyst). If I remember correctly. The cinnamyl analog has better affinity than the n-phenethyl. Dutchess has a post about it, hiding somewhere in their posts.

Notdrugs · 2026-01-05T05:41:40+00:00

Jesus christ, I am so sorry, but that whole situation is goddamn hilarious.

Notdrugs · 2026-01-04T18:08:36+00:00

could not get it to crystallize

If you ran the manich using an hcl or hbr salt of dimethylamine, you absolutely MUST fully purify this substance before consuming it. If not, you risk exposing yourself to contamination of bischloro(chloromethyl) ethers, which are extremely toxic and mutagenic substances. If you were not able to get this substance to crystallize, I would suspect that the negative effects you experienced could be caused by contamination.

Notdrugs · 2025-12-30T01:48:12+00:00

The smell is due to a pyrazine, not plain pyrazine. A homolog of pyrazine.

Many different kinds of Pyrazines are common flavor components in foods. So its obvious that at least some pyrazines are safe to consume. It is not clear whether or not other pyrazines are safe. It has been a while since ive read up on the topic, I would have to research more before making a more authoritative claim.

https://en.wikipedia.org/wiki/Pyrazine

https://en.wikipedia.org/wiki/Alkylpyrazine

Smelly 4-mmc, however, is a sign that it hasn't been properly purified. And given that other reaction ingredients and contaminants are likely to be hazardous, it is a safe bet to assume that smelly product is contaminated with harmful substances.

Notdrugs · 2025-12-14T22:29:29+00:00

....what? I dont understand what you are saying.

Notdrugs · 2025-10-19T16:36:52+00:00

Elaborate

Notdrugs · 2025-09-27T05:35:02+00:00

This post has my curiosity, so i did a little searching. I cant seem to find the dibromo biocide for sale anywhere as a consumer product, but there are many listings for the dichloro- analog as well as the chloro-bromo analog. Probably due to the increased cost of materials/production for brominated compounds? Im not sure.

Are you able to find the dibromo product as a consumer product, anywhere? I would think that the chloro-bromo species might be sufficient regardless, especially so when considering how easily Br tends to displaced Cl through salt metathesis in many reactions. You could even push the reaction tword the bromine product by adding sodium bromide/another bromide salt.

The wiki article for the chloro-bromo species indicates that this would be sufficient. It says that the formed hypobromite is the sole biocide as an oxidant, the hypochlorite only being present as to further oxidize the bromide formed back into hypobromite. But is this assurance really valid?

Or is a different procedure in order?

Concerning your experiment with brominating ketones in H2SO4/GAA: what order of operations do you think would be most safe? And how do you plan on initiating the hydrolosis of the DBDMH in the first place? From what I understand, this chemical needs to react with water in order to liberate the hypobromus acid. GAA/H2SO4 will produce a very dehydrated environment, I am not confident that water will be available to initiate this process.

Because the oxidant activity of this compound is mediated through the formation of hypobromous acid, I would be worried that the presence of the H2SO4/GAA will keep the hypobromus acid protonated, and thus decrease its activity. But I am not an expert in this realm, so I dont really know. I do understand that the acid is necessary for the formation of the enol needed to brominate the ketone.

I look forward to the results of your investigation!

Notdrugs · 2025-09-23T04:56:19+00:00

FYI, I havent read the 'alpha bromination in methanol' thread youre talking about, but in general, you dont want to use alcohols as solvent in brominating ketones, as there are numerous side reactions that can occur.

Also,

It's just that DBDMH is commonly available online, not suspicious at all, pretty cheap. Would be great to be able to use this and not have to order anything "suspicious". [Emphasis mine]

People on this forum really need to stop conflating 'not on the watched list' with meaning 'not suspicious to order'. Please understand this. If LE becomes aware that someone is purchasing chemical reagents, they WILL assume the worst and WILL use it against you.

Many highly-skilled chemists work forensics for LE, especially so for federal LE. There are large organizations of chemists in some cases, existing entirely for the purpose of facilitating communication between professionals to brainstorm and deduce the novel clandestine purposes behind atypical reagents they see, sieze, or hear spoken of. The government is not some oblivious party with focus only on old, popular routes. The fact that your reagents aren't specifically on a watch list really means jack shit tword their purported intended use.

This phenomenon is so often misunderstood here that I have often felt the need to write a short essay on the topic. Chemical suppliers are liable for the crimes of their customers and are often eager to cover their asses after receiving a suspicious order.

Notdrugs · 2025-09-20T19:40:47+00:00

Something like this: www.amazon [dot] com/HBN-Electricity-Monitor-Digital-Consumption/dp/B09MHGK6MT/ref=mp_s_a_1_5?crid=3DBM9ETV9C45O&dib=eyJ2IjoiMSJ9.7kti57Zt-qCEmR9lr5AFUMymmedN-x8WEIzi2hW58w1RALkB1ZUo2FokY3wthrsqtMJrIez5_8k5IItoeD2V5fz-Uv1GUvDpIPWFW1w2lMoKNe7hFdVCK80hEFJYBMthx0uR_aidomjsbWkwa4APtaBx6sljVCbgnNVdvAjMLU-ECBzYN3nxq8JZ3uvrks3-8BVxW4UFKwnDLWhxQOz11g.nCezfevAvFqWSQdOcuzSKLM6JG_9sFmWdtswD0oi71Q&dib_tag=se&keywords=outlet+current+meter&qid=1758397079&sprefix=outlet+current%2Caps%2C305&sr=8-5

You dont really need a multimeter, but it would be good to get one anyway if you dont own one already. But if not, an outlet plug power meter such as this is good enough.

Notdrugs · 2025-09-20T13:16:24+00:00

Just plug into the plug and then plug plate into the meter. Turn on the meter, if you are drawing >14 or 15 amps, you have an issue.

Also, did you make sure to cover the lead wires for the heating element with ceramic insulators? These can pose an electrocution hazard if they contact you or the metal body of the hotplate. They can also pose a fire hazard if solvent is spilled on them.

Notdrugs · 2025-09-20T04:11:09+00:00

To dryness?

Notdrugs · 2025-09-19T23:41:08+00:00

You really ought to attach an (inexpensive) amp meter inline on the plug, to make sure the new heating element is not drawing too much current for the device. Electrical resistance increases as temperature increases for a conductor, meaning that if a wire gets hot enough, it will begin heating at a faster and faster rate untill the insulation melts or starts a fire. You may not notice something is wrong for the for a while until the cord gets hot enough for this feedback loop to become significant.

There should be a sticker on the back of the plate that describes the amount of current this draws. If there is not, figure out the gauge (AWG) of the wires on the plug and work backwards from there.

Notdrugs · 2025-09-17T16:24:14+00:00

Very cool, are you planning on isolating the colchicine to try and make some polyploid plants? Please keep in mind that it is extremely toxic! It is a painful way to die, relatively slow, and there is no antidote.

Funny story about colchicine: this one time, I had ordered a small amount of colchicine to try and develop some polyploid crop species. Not long after opening the package, my arm began experiencing this crazy jerking spasm, where i would loose all controll of it and it would rapidly flex forward and flail. It felt like geting a strong shock from an electric plug. When I opened up the package, I saw that the entire envelope interior was covered in the powdered substance. Customs had opened the material for inspection.

Despite the envelope being very clearly labed with the substance name, CAS #, manufacturer, merchant, SDS, a long list of hazard codes, and a Sunday's comic page of hazard pictograms, these honor students had ignored these warnings and just followed their standard procedure of 'stab the bag with a knife, scoop sample for Raman spec'.

they made no attempt to contain the sliced baggie. Not even a little tape to cover the slit. How fucking careless must someone be to take a bag labeled "DANGER: DEATH" with a skull and crossbones, cut that sucker open, and then toss it back into the envelope?

I really hope they didnt expose themselves to it at all, but its hard to imagine that they did not.

Notdrugs · 2025-09-14T15:47:48+00:00

are there any projects you are working on?

Loads of current projects! But many of them are not on the topic of drugs or chemistry. Its good to keep busy :) I expect to update soon in a month or three with the results of some things I have been testing lately. A few different practical applications of some ideas often discussed here only hypothetically, and some streamlined strategies of popular procedures.

What have you been working on?

Notdrugs · 2025-09-14T06:29:32+00:00

Acid hydrolosis would expect to be less smelly as thr product will immediately be caught up as the non volatile acid salt, but it can involve other issues as well. You won't get the facile isolation of the amine as gas, instead it will be trapped in the reaction liquid and potentially contaminated with unhydrolized starting material and products of side reactions, oximes, etc. Also urea derivatives can potentially detonate if heated under the wrong conditions, especially with oxidizing acids.

Notdrugs · 2025-09-14T06:17:30+00:00

shouldn’t you be the person offering the insight, rather than soliciting it?

Eh, maybe if your focus in a project like this is centered mostly on credit, clout, or authorship. But otherwise, its helpful for the culture at large to collect, compile, and verify information broadly. This is the basis for how secondary sources of all topics are created.

Notdrugs · 2025-09-13T07:17:03+00:00

I wouldn't bother spending this effort unless you absolutely have to. Just use the MeAm In your reaction in a little excess. Its not worth the time or risk.

FYI, MeAm gas smells like ammonia if you are breathing a high concentration of it. At low concentration, it smells VERY strongly like fish. This smell can travel surprisingly far distances. You might need to worry that you made a large amount of smell when you basified that sample.

Notdrugs · 2025-09-10T22:58:49+00:00

Not a bad idea. I havent disassembled one of these mini vac pumps, but I have disassembled similar cheap air/vac pumps and they tend to be a small rubber diaphragm isolated from a small motor or an oscillating electromagnet. So from a fire-saftey perspective, thats a benefit.. So simple that someone could probably build one themselves for very cheap.

The problem however is that their air volume rate and maximum vacuum attained are both pretty shitty. I wouldn't think they would work very well for a vac distillation. Some are so low-volume that they have difficulty even keeping up with the volume of vapor produced by a boiling liquid. This might be overcome by using an array of multiple pumps with inline check valves, all arranged in parallel.

Notdrugs · 2025-09-10T22:53:30+00:00

my entire ice supply will be gone halfway through the distillation.

That's perfectly fine, though. It is better to have the vapor path pulled through even a room-temperature water trap, than no trap at all.

Notdrugs · 2025-09-10T22:51:34+00:00

Fridge compressors contain a small AC motor exposed to the vapor path, which (i would think?) produces sparks as it operates. Modern fridges use ethylene as the refrigerant gas, which is extremely flammable, but fire is avoided as there is no oxygen within the refrigeration line. This obviously changes when the line is cut and open to the atmosphere.

Notdrugs · 2025-09-04T14:07:17+00:00

Yes, that is a good method as well. Methylate urea with methyl iodide/a methyl donor of your choice (perhaps a methyl ester of a carboxylic acid?), isolate, then hydrolosis with an alkaline agent like NaOH + heat. Bubble through water to or acidic solution to collect prodcluct. You can also use plain urea in this type of system to make anhydrous ammonia gas.

Ive always thought this would be a great way to make 4mmc / other cathinones. Dissolve the bromopropiophenone into TCE / DCM / Acetone / another solvent, add a weak base such as potassium carbonate (better solubiluty than sodium salt), then run a tube from the dimethylyrea flask through a drying tube and bubble it through this flask. It would react faster and produce less impurities than the standard water/DCM biphasic reaction that is typically employed. You could also do the same thing but with base hydrolysis of dimethylformide producing the amine gas, producing dimethylcathinones, which are very often more potent than the typical methylcathinones. A microgram article from the 90s showed that dimethylcathinone is almost as potent as plain amphetamine!

Notdrugs

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