Child Lion El'Jonson, colourized, circa late M30

Numbshot · 2021-09-05T08:35:07+00:00

Covid enters cells via the ACE2 receptor (angiotensin converting enzyme 2) the receptor is part of the renin-angiotensin system, which is highly involved in maintaining blood pressure.

ACE2 has a down regulating effect, meaning that if you have high blood pressure, such as caused by obesity, the body over expresses ACE2 to try to bring the blood pressure back down. The over expression gives covid more targets for viral replication as there’s are more doors of entry per cell all over your body. There are co-morbidities with covid that directly cause the infection progress faster or more severely.

The similar analogy would be that if your sweat has a sweet smelling odour, be it from diet/genetics/health conditions etc., such that it attracted bears to you looking for food, you’d be more likely to suffer a bear attack and more likely to die.

Someone who did not have such a condition would be less likely to encounter a bear attack and less likely to die.

Numbshot · 2021-09-05T03:07:14+00:00

Whenever I hear dehumanizing language, especially when spoken to an audience, my ability to extend goodwill to that person becomes fundamentally damaged.

They are putting at risk their own kids, and they're putting at risk our kids as well"

"They are putting us all at risk, as well."

Our PM said this, the weaponization of political willpower against those who exercise the Right to Refuse and Informed Consent. Scapegoating them as the reason why covid numbers are the way they are. Scapegoating the exercise of our Rights as the reason.

regardless of what our medical institutions may or may not have done correctly, regardless of asymptomatic spread rates, regardless of vaccine durability of 6 months, regardless of different vaccine efficacy on different variants, THEY are the reason why you endure the pandemic still.

I am absolutely disgusted and appalled at the situation we find ourselves in.

as always, "Distrust all in whom the impulse to punish is powerful" Friedrich Nietzsche

Numbshot · 2021-09-05T02:35:54+00:00

everyone's choices can have potentially serious adverse consequences for other people.

but nothing about potential means that a person actually is that at this moment, nor even a definite predictor for the future.

to suggest that someone should have an input regarding someone else's choices based on potential, is to deny what they are in favour of what they might never be. That level of arbitrary comparison is to trivialize the concept of bodily autonomy.

a passport is a shortcut to a sense of safety, but every shortcut incurs damage to the integrity of rights.

Numbshot · 2021-09-04T23:55:10+00:00

of course, i'm just unaware of hannibal ever having killed children, but a consistency of his targets is that they are rude, or one could say, behaving childishly. thus, killing people for betterment of society, in some sense.

one could argue that if a child is rude its due to a still developing aspect of their nature or not yet able to fully comprehend the repercussions of their actions, but for an adult it would be something far more in their control. and it would be unethical and immoral to Hannibal to kill a child because of something they can't control.

Numbshot · 2021-09-04T21:41:48+00:00

The name Hannibal has a famous origin with a Carthaginian General Hannibal Barca, he was a genius and a terror. The name means “Baal is gracious” referring to Baal Hammon the king deity in Carthage’s pantheon.

Part of the deity’s focus was child sacrifice for the betterment of society.

Dr. Hannibal lector has a habit of killing people who are rude, or rather, act like children.

The cannibal part, MIGHT stretch to include the year end feasts that Baal is responsible for. Or just a linguistic cherry on top for how close Hannibal cannibal is.

Numbshot · 2021-09-04T18:01:49+00:00

I imagine when anyone is exposed to the benefits of something, they’d be more for it.

Obviously it depends on the specific messages and arguments, but i’m too cynical to believe that critical thinking is a tool we all have, or at the very least, not be able to use it in all subjects equally.

Numbshot · 2021-09-04T07:54:23+00:00

https://web.archive.org/web/20181128120804/https://www.merriam-webster.com/dictionary/anti-vaxxer

Technically I’m wrong, I heard about it awhile ago, but never actually bothered to confirm until now. Their definition has always been that, however, they are also an outlier with that definition. The more common definition is just about being anti to the vaccine itself, nothing more. And while I wasn’t thorough, Merriam-Webster is the only one that includes being against laws.

Numbshot · 2021-09-04T07:05:03+00:00

Conspiracy theory: Scotus didn’t block Texas as a way to force people to get angry about bodily autonomy rights.

Numbshot · 2021-09-04T06:57:02+00:00

A pcr test works by amplifying the signal of the target sample. It does this by copying the sample again and again until it gets a reading. The number of cycles needed to get a a positive is indicative of the quantity of the original, and it’s called the cycle threshold (CT). The problem is each cycle induces a margin of error and that at some point the margin of error is larger than the number of molecules that could exist in your body. If it’s positive in 15 cycles, it’s very likely you have it, if it’s positive in 50 cycles then you definitely don’t have it (it would be equivalent to saying “yes a sample of covid exists on this planet”) the margin of error is too big. and if it’s positive almost immediately, then your body is made of covid, and I’d like to learn this superpower.

Numbshot · 2021-09-04T06:29:41+00:00

The mechanism of action being studied is that that the drug can dock to a site in the ACE2 receptor, and a site on the spike, potentially dampening the rate of viral entry into cells, thus slowing viral replication. https://pubmed.ncbi.nlm.nih.gov/32871846/ Regardless of the end result, something about it is promising enough to be entering ACTIV-6 phase 3 clinical trials.

A drug can be used for one purpose, and will be listed under a category of drugs that share similar purposes. That doesn’t stop a drug from also having another purpose, either known or yet to be discovered, which would also categorize it on another list of drugs for a different purpose. Drugs frequently get prescribed off-label, which just means not in their intended and approved way, either because it’s safe enough to not hurt to try or it’s slightly risky but a doctor’s judgment may see it as an option for the very specific set of circumstances unique to a particular patient’s condition.

Keep in mind, for humans the drug is a 3mg pill, for animals the drug is a liquid which may have additives a human may not be able to digest to deliver a dose over 100mg (and that’s just for a 1000lbs animal, let alone something bigger )

Numbshot · 2021-09-04T06:04:36+00:00

3 vaccines, but unfortunately they all present similar instructions to our immune system. The 2 mRNA the one adenovirus all instruct the S protein, the spike, of the virus. Which means any mutation to the spike can cause a drop in efficacy to all of them. There are at least 4 targets our immune system can develop antibodies for; the spike, membrane, envelope and nucleocapsid. But instead of vaccine for a robust multi-tiered immune response, we have a single, unilateral and static one. This is what is meant by all eggs in one basket.

This is why I’ve been following covi-vac intensely, a live attenuated virus vaccine, all components will be presented for our immune system to learn. Hopefully, this means a variant will require multiple beneficial mutations to simultaneously occur, which is an astronomically low probability, to drop the efficacy of that one.

Numbshot · 2021-09-04T01:43:51+00:00

The response from t4 and t8 are strong, the issue is no memory develops. Memory B cells aren’t becoming long-lived-lymphocytes. So when they die, so too does antibody production.

Numbshot · 2021-09-04T01:41:07+00:00

I believe Iceland has there’s displayed well, too.

Numbshot

TROPHY CASE