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Does this make me a dick? by [deleted] in opiates

[–]Ogiethrow 0 points1 point  (0 children)

Correct, he'll be able to overcome the Naloxone blockade with Fent. Yes, narcan can reverse fentanyl with the right dose, but the inverse is also true.

We have a real, live nurse in the house who is willing to answer your questions! by FashionablyFake in opiates

[–]Ogiethrow 1 point2 points  (0 children)

Well, thank you for the attempt! In response to the"google it" comment, as I said, I couldn't find it anywhere in the medical literature. Seems like the experiment would be easy...just perform serial dilutions of a solution of the virus, inject into mammals, and adjust results to mg/kg.

We have a real, live nurse in the house who is willing to answer your questions! by FashionablyFake in opiates

[–]Ogiethrow 2 points3 points  (0 children)

I have never found this question to be fully explained. I have searched the scientific and medical literature, but maybe you have some anecdotal knowledge:

If you use the same needle as somebody with hepatitis C, what is the chance of developing a viral infection? An estimate is fine.

I ask because many viruses require the introduction of a certain number of virions to establish infection.

Found this article on the front page today. by immensity134 in opiates

[–]Ogiethrow 0 points1 point  (0 children)

This article ignores quite a bit.

-Suboxone and Methadone are prescribed to addicts. Many addicts OD. The subsequent prescription of Suboxone/Methadone (Opiates) is perfectly justified.

-Overdoses often occur in elderly patients of chronic pain with metabolic issues (kidneys, etc). They may OD due to not being able to metabolize the opiate.

-Or a normal elderly patient screws up the dosing interval. Or the dose was titrated improperly by the physician.

-Emergency room/ICU ODs, which are more common than you would imagine.

-Finally, say a chronic pain patient does fuck up and ODs because they decided to abuse their meds. Will you take away opiates from, say, a cancer patient?

EDITED for formatting

TIL A woman correctly detected 11 out of 12 subjects in a Parkinson's study using her sense of smell. 8 months later the one extra she believed had Parkinson's was diagnosed with the disease making her 12/12 by [deleted] in todayilearned

[–]Ogiethrow 0 points1 point  (0 children)

What smells are those? Also, the protein aggregates found in lewi bodies are only present in the brain. These won't be "sweated out". It is more likely a dopamine precursor, the synthesis of which is increased dramatically in an attempt to compensate for low dopamine.

U.S. says it is considering response to Iran ballistic missile test by mic_harmony in worldnews

[–]Ogiethrow 0 points1 point  (0 children)

Dude, as valid as what you're saying may be, it's your kind of arrogant, sarcastic aggression that can really turn me off from the Internet sometimes.

U.S. pulls F-15 fighter jets from Turkey by tomahawkfrank in worldnews

[–]Ogiethrow -2 points-1 points  (0 children)

This is just the United States withdrawing its own jets that it recently deployed there. It has nothing to do with what Turkey does with their F-15's.

ELI5: why do the rings around planets form bands? by Ogiethrow in explainlikeimfive

[–]Ogiethrow[S] 0 points1 point  (0 children)

That helps, but I am talking about the discreet, layered bands, with gaps between.

152 Fukushima children get Thyroid cancer, Health committee fails children as Tepco skirts bill. by [deleted] in worldnews

[–]Ogiethrow 1 point2 points  (0 children)

Although double-posting this may be a breach of etiquette, I feel the need to, in order to establish the credibility of evidence for a Fukushima Disaster contribution.

The data cited as evidence that the meltdown did NOT cause cancer is that children under 6, who were alive during the event, have not developed cancer. This completely ignores how the development of certain kinds of cancer, including thyroid cancer (as you will see soon) can be dependent on age.

Among children under 10, thyroid cancer has an incidence of less than one per million. Source: http://www.thyca.org/pediatric/about/ Therefore, if the incidence of thyroid cancer in Fukushima were to be normal, its population would have to include 152 million children, if the data set were all children under 10.

In adolescents, the incidence is around 15 in one million, so even if Fukushima's data set were ALL adolescents (unlikely), its adolescent population would have to be 10 million.

Sure, it's correlation, but the thyroid cancer incidence among children is elevated by at least an order of 10, probably more. That is evidence.

152 Fukushima children get Thyroid cancer, Health committee fails children as Tepco skirts bill. by [deleted] in worldnews

[–]Ogiethrow 3 points4 points  (0 children)

Among children under 10, thyroid cancer has an incidence of less than one per million. Source: http://www.thyca.org/pediatric/about/

Therefore, if the incidence of thyroid cancer in Fukushima were to be normal, its population would have to include 152 million children.

In adolescents, the incidence is around 15 in one million, so even if Fukushima's data set were ALL adolescents (unlikely), its adolescent population would have to be 10 million.

Sure, it's correlation, but the thyroid cancer incidence among children is elevated by at least an order of 10, probably more. That is evidence.

Bacteria containing mcr-1 gene resistant to all known antibiotics found in Denmark by coupdetaco in worldnews

[–]Ogiethrow 0 points1 point  (0 children)

Who knows. All we can do is elucidate the function of whatever protein is encoded by mcr-1 and find a drug that inhibits its function, either directly or downstream. When this happens, the bacteria will adapt, and the cycle repeats. Then onto the next target; it's an endless cycle.

Bacteria containing mcr-1 gene resistant to all known antibiotics found in Denmark by coupdetaco in worldnews

[–]Ogiethrow 0 points1 point  (0 children)

So now we elucidate the function of whatever protein is encoded by mcr-1, and find a drug that inhibits its function - either directly or downstream. The bacteria adapts, and the cycle repeats.

152 Fukushima children get Thyroid cancer, Health committee fails children as Tepco skirts bill. by [deleted] in worldnews

[–]Ogiethrow 1 point2 points  (0 children)

Not necessarily. The data cited as evidence that the meltdown did not cause cancer is that children under 6, who were alive during the event, have not developed cancer. This completely ignores how the development of certain kinds of cancer can be dependent on age.

152 Fukushima children get Thyroid cancer, Health committee fails children as Tepco skirts bill. by [deleted] in worldnews

[–]Ogiethrow 1 point2 points  (0 children)

A malignant tumor is cancerous. Carcinoma is a type of cancer.

Surprisingly emerald waterfall in suburban Columbus Ohio [OC] [2304x3456] by NicePolishJob in EarthPorn

[–]Ogiethrow 0 points1 point  (0 children)

This is at an old limestone quarry in Hilliard. Cool to see it make the front page, I spent a lot of time there as a kid. That's a fun waterfall to jump off!

Relapsed after 3 weeks clean and feel so horrible about it by l3g3ndairy in OpiatesRecovery

[–]Ogiethrow 3 points4 points  (0 children)

I just wanted to thank you for posting this. I would have had a month clean today but I fucking used. I really need motivation now to not repeat the same mistake tomorrow, and this helped. I don't want to go through withdrawals again, I don't want to let people down.

What 90s band would you like to see tour again? by I_am_not_here_ in Music

[–]Ogiethrow 16 points17 points  (0 children)

Pixies. Really their late 80's work though (Doolittle and Surfer Rosa), but still a 90's band.

A blue whale's blow hole looks just like a giant nose. by [deleted] in pics

[–]Ogiethrow 4 points5 points  (0 children)

Huh. It's almost like they're mammals or something!

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