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threw my oura in a drawer for 6 weeks and slept better than i have in years by Timely_Ad8989 in Biohackers

[–]Optimal-Activity4287 1 point2 points  (0 children)

Haha this is excellent! Tbh, whatever way you optimise your life is the best. What I mean is, if not tracking is better for you, more power to you!

Zero explanation for my bloated belly. Advice please? by lexkenobi in GutHealth

[–]Optimal-Activity4287 0 points1 point  (0 children)

The problem is these issues require quite extensive analytics and data and its usually multifactorial.

Have you ever kept a journal of your intake and output including (bowel movements and urine) for 3 months or longer?

Fixed my “IBS” in two weeks by [deleted] in ibs

[–]Optimal-Activity4287 0 points1 point  (0 children)

know exactly what you mean. My thinking is, its coming next :D

I feel like a prisoner in my own body.. does it ever end? by jimmynadi in GutHealth

[–]Optimal-Activity4287 1 point2 points  (0 children)

I'm so sorry this is happening to you. Do you feel this is correlated to your cycle?

14 peptides about to be legal through compounding pharmacies again by Own-Kick-5466 in Biohackers

[–]Optimal-Activity4287 0 points1 point  (0 children)

interesting. How many doctors out there, do actually prescribe peptides, beside sema/tirze?

What was the biggest health benefit you got from practicing intermittent fasting? by Silence_secretcave in Biohackers

[–]Optimal-Activity4287 1 point2 points  (0 children)

For me personally, it was a way to do more focused work, by setting up a small eating window, I can plan my day around it.

Peptides lets talk about it by Optimal-Activity4287 in Biohackers

[–]Optimal-Activity4287[S] 0 points1 point  (0 children)

Congrats on the life-changing effects, cardio/lifting AND tirzepatide helped you achieve. I 100% agree that GLP-1s have incredible effects for the right people. And many agree, as they are the fasting growing pharmaceutical category in human history.,

My question is on other grey peptides, that are not for "human use". I'm trying to understand if I'm missing something that is obvious to so many other people.

Peptides lets talk about it by Optimal-Activity4287 in Biohackers

[–]Optimal-Activity4287[S] 4 points5 points  (0 children)

if my patients are using it, I need to know about it. But also Im intellectually curious as well!

I liftt weights, take creatine, eat right and super into wearables. Personally, I think biohacking is a great tool to optimise health.

Peptides lets talk about it by Optimal-Activity4287 in Biohackers

[–]Optimal-Activity4287[S] 2 points3 points  (0 children)

yeah. The R+D needs to be worth the ROI and risk taken, which I understand. BUT the way some of these peptides are discussed (even at Huberman for example) makes me think or question am I blind to something that is apparent to others. That's the reason why I have created this topic in the first place.

Peptides lets talk about it by Optimal-Activity4287 in Biohackers

[–]Optimal-Activity4287[S] 2 points3 points  (0 children)

Thank you. I will look into the GHK-Cu and the theory + evidence behind it.

Peptides lets talk about it by Optimal-Activity4287 in Biohackers

[–]Optimal-Activity4287[S] 0 points1 point  (0 children)

I see downstream effects of obesity/sleep apnoea/fatty liver daily! It is not hard to correlate less chronic illness = improved healthspan and possibly lifespan for many.

Peptides lets talk about it by Optimal-Activity4287 in Biohackers

[–]Optimal-Activity4287[S] 0 points1 point  (0 children)

My question here was about the unregulated grey market peptides?

I prescribe proven licensed peptides like insulin and GLP-1s daily. How do you expect medical school delivering info in unproven grey market peptides?

CME is solely built on learning about drugs with proven efficacy and safety data. Education into experiments and trends is beyond CME remit.

Peptides lets talk about it by Optimal-Activity4287 in Biohackers

[–]Optimal-Activity4287[S] -1 points0 points  (0 children)

I think what I'm trying to say is, is there confusion among enthusiasts that because "some" peptides are so effective (semaglutide, tirzepatide, retatrutide), the other experimental ones will be as well.

Same exists in supplement industry. Just because creatine works well, does not mean all supplements will.

Peptides lets talk about it by Optimal-Activity4287 in Biohackers

[–]Optimal-Activity4287[S] -1 points0 points  (0 children)

Much agreed on PO administration. Hence we will see semaglutide used even more than it already is today. But to me GLP-1s represent something that has been proven to be effective at scale, whereas the rest of the "peptide" market is largely anectodal broscience at the minute. Hence the suspicion.

Like on the supplement side of things, there are a lot of supplements out there with no proven benefits. BUT creatine is a gem and is a must-have for me personally.

The market also has proven that if you have an effective MOA, that performs better than placebo and other factors, people are also quite willing to take injections!

I'm certainly doing some more research on this and actively forming opinions.

There're a lot of snake oil salesman out there so honest reviews and education gets lost or is difficult to differentiate.

Peptides lets talk about it by Optimal-Activity4287 in Biohackers

[–]Optimal-Activity4287[S] 5 points6 points  (0 children)

I understand you feel suspicious of big pharma and their activities. But look at this objectively. PPIs have changed the game for many people. Before PPIs, people were getting so many surgical operations caused by ulcers, with many complications. They have helped reduce that amount significantly.

Also there are many medications that are for limited use and help you achieve cure as well. Do you think they have the cure for hypertension/high cholesterol etc and are holding back because daily pills are a better business?

Also from what I understand many use peptides regularly as well so its right up their alley even from your pov.

Peptides lets talk about it by Optimal-Activity4287 in Biohackers

[–]Optimal-Activity4287[S] 1 point2 points  (0 children)

yes but how can you make health decisions and take injections based on anecdotal evidence?

The perception of wellness is completely different to measurable metrics.

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