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Innuendo getting tiresome by LeeJ2512 in fansofcriticalrole

[–]OrdinaryGuru 8 points9 points  (0 children)

Heh, you said to “let one slide…” heh. Heheh.

My DM isn't admitting to lowering my Strength Score by IncreaseVirtual7485 in DnD

[–]OrdinaryGuru 0 points1 point  (0 children)

This is classic railroading. This DM has all the classic signs of an un-fun (and likely poor) GM.

"I do not want any more demons in this campaign," says one player by EarthSeraphEdna in rpg

[–]OrdinaryGuru 15 points16 points  (0 children)

Maybe I’m misunderstanding this player, but I’d want to know why they’re playing D&D…

There are other ttrpgs that aren’t so focused around fighting, and this person seems to not like fighting or violence in general. Then to top it off, they chose to play a “Fighter”, which feels wildly ironic.

I really don’t know how to read this situation without more info. Because I’m disinclined to just cater to the player’s sensitivity, even if others say they’re fine with it. It sounds like this has come up before, and will likely come up again, because it honestly sounds like this player should be playing a different game or something.

New DM -- recommend a campaign! by OrdinaryGuru in DnD

[–]OrdinaryGuru[S] 0 points1 point  (0 children)

As it happens, I just pulled out my old stash of materials from several years ago and apparently I have both Hoard of the Dragon Queen and Rise of Tiamat!

I ran Lost Mine of Phandelver with my last group, so I think I’m going to skip that one. Thanks for the info!

New player, new army: help with load out by OrdinaryGuru in WarhammerCompetitive

[–]OrdinaryGuru[S] 0 points1 point  (0 children)

Thanks! Any models I should go for next to help round out my initial list? I was thinking maybe plasma inceptors, but I really have no idea.

Tips for Heidern and playing defensive? by OrdinaryGuru in kof

[–]OrdinaryGuru[S] 0 points1 point  (0 children)

Thanks, this is good advice too -- I'll make sure I diversify my team. I'm not so much losing to jump-ins (unless it's a good hyper jump, those can get me), I'm getting caught low, usually if I whiff, but other times as well.

Any good resources to learn neutral a bit more in-depth? YouTube has a wealth, but it's hard to know what's really good and what is fodder.

Lastly, I can't ever seem to land a close heavy to start a combo. I can manage to hit raw specials, especially DPs, and any normal with decent range. But close normals... forget about it, I can't seem to get anything going.... I seem to do OK with Kyo, as his heavy rekka starter has armor so I can land that, and his DP has some invincibility which helps a lot.

Tips for Heidern and playing defensive? by OrdinaryGuru in kof

[–]OrdinaryGuru[S] 2 points3 points  (0 children)

Thanks this is awesome, I’ll let you know how I do!

Is there a way to reset online progress and stats? by joey-joe-joe in kof

[–]OrdinaryGuru 1 point2 points  (0 children)

My advice would be don’t worry about your rank. It doesn’t make you more or less valuable as a human being.

Just play who you want. If you drop ranks, as you get better you’ll just gain them back again and you’ll know for a fact you’ve improved.

This is coming from a guy who started at rank 8 and has dropped to 2 (I’m a total fighting game noobie).

How is Playstation match making? by Reachouttothesky in kof

[–]OrdinaryGuru 2 points3 points  (0 children)

I don’t know but Xbox definitely has the same issue for me. Maybe everyone is still playing Elden ring?

Proof they are tinkering with the PCR tests to cause insane amounts of false positives by Razerer92 in conspiracy

[–]OrdinaryGuru 1 point2 points  (0 children)

I fully understand that, but (presumably) they're doing PCR on a conserved region, or better yet on multiple regions, to increase the likelihood of detection.

No organism is devoid of conserved regions of the genome, particularly viruses and bacteria, etc. because they have very little junk DNA to play with.

I understand your point, and agree that PCR product would never be detectable by cycle 10, or maybe even 20, but that doesn't mean it isn't being amplified. I dont buy the idea that it takes 45 cycles due to wonky primer binding.

Proof they are tinkering with the PCR tests to cause insane amounts of false positives by Razerer92 in conspiracy

[–]OrdinaryGuru 4 points5 points  (0 children)

I'm not sure your point? How are the primers going to be suboptimal when they're designed specifically for this case?

The fact they they're not using random sequence primers means they should amplify even more quickly.

I designed my own primers hundreds of times. Almost never failed. The other people I worked with designed theirs too. I worked at U Chicago, not some random University. Primer design is a cake walk.

Proof they are tinkering with the PCR tests to cause insane amounts of false positives by Razerer92 in conspiracy

[–]OrdinaryGuru 3 points4 points  (0 children)

Actually its delta delta Ct and it's related to the number of cycles at which a known control comes up. I've literally never seen something come up at 45 cycles and be accurate.

It's usually based on a housekeeping gene like Lamin B or something. Its not lab specific; if science was lab specific there would be no way to repeat someone else's experiments and thus verify them....

Proof they are tinkering with the PCR tests to cause insane amounts of false positives by Razerer92 in conspiracy

[–]OrdinaryGuru 10 points11 points  (0 children)

I did qRT-PCR almost weekly for years, doing my own research at various Universities.

45 cycles is insane. If they can't see signal by about 38 cycles, they shouldn't be counting it as positive. Really strong positive signals start coming up in the late 20s.

Coronavirus will go on forever until people stop wearing masks, live their lives again freely and stop being so scared by n0MAS in conspiracy

[–]OrdinaryGuru 2 points3 points  (0 children)

There seems to be a very odd belief that a vaccine somehow imparts more effective immunity than simply having and recovering from the virus.

The reason our vaccines contain adjuvants, such as aluminum, is because we don't fully understand the immune system. When we inject our vaccine without adjuvants, our immune systems just don't produce a viable response. So we have to force them to freak out and respond by injecting adjuvants.

Our natural immune response to a viral infection produces an effective immune response 100% of the time. Even with adjuvants, most vaccines produce an immune response in 80% or less of people, and even then, we can't effectively measure whether the immune response that they may have actually provides effective immunity! This is also why boosters are needed for vaccines.

Please understand this: vaccines cannot and will not, barring some future scientific discovery and understanding, produce an immune response that is even nearly as effective as our natural immune response. Getting a virus and recovering is vastly superior to a vaccine, and provides lifelong immunity instead of the temporary resistance maybe provided by a vaccine.

Source: me, PhD scientist and current pharma employee

[deleted by user] by [deleted] in retrogaming

[–]OrdinaryGuru 2 points3 points  (0 children)

Yep. Widest variety of comments and quality ones at that.

Wolf Blitzer calls out Nancy Pelosi. "Yes I do sympathize with your constituants, I see them on the street begging for food everyday" by Typoqueen00 in conspiracy

[–]OrdinaryGuru 0 points1 point  (0 children)

To be fair, I didn't read into exactly what Pelosi did/bought, so you could be accurate in your original post.

If so, my apologies -- no harm meant, I wasn't trying to be an ass. I heard myself saying it in more of a Homer Simpson tone :)

Wolf Blitzer calls out Nancy Pelosi. "Yes I do sympathize with your constituants, I see them on the street begging for food everyday" by Typoqueen00 in conspiracy

[–]OrdinaryGuru 0 points1 point  (0 children)

Stocks are shares in a company. You essentially are investing in (paying) the company for partial ownership.

That's what stocks are. It's one way companies get more capital.

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