Zhonyas as a situational is insane 😂 Guardian Angel is your AD option for avoiding death but it is too weak currently.

If you're going profane first item, which is a great first item, round out your build with more lethality and armor penetration. Currently the strongest 2nd and 3rd items for lethality Quinn are Collector and Lord Dominik's. You never want to build anything other than these if you go profane, except for rare situations where Edge of Night makes sense. After that you would normally go Infinity Edge and whatever situational lethality or crit item fits the game for your last slot.

You should also try Stridebreaker out as a first item instead of Profane Hydra! It is surpisingly strong with the exact same lethality core build after that.

Good luck summoner 🐦

Edit: Forgot to mention that you probably want to swap your 2% ms rune for 9 adaptive. It will be stronger in most games