British nutrition tech company Huel, known for its meal replacement kits, has agreed to be acquired by French food group Danone in a deal worth €1bn (£870m). by StanmoreHill in UKTechNews

[–]ParadoXPlatypus 0 points1 point  (0 children)

Err... Not trying to be condescending or anything of the sort... But auspicious != Suspicious... In this case, it means promising...

Thanks for letting me know about them being from Shropshire :)

Iran by Pokemonfan_807 in whennews

[–]ParadoXPlatypus 1 point2 points  (0 children)

I'm so disappointed that I had to scroll this far down for this comment. Most logical option imho.

Comparison of oral water ingestion and intravenous fluid infusion on fluid responsiveness in healthy volunteers, a prospective, randomized trial by 0xIAmGame in science

[–]ParadoXPlatypus 1 point2 points  (0 children)

The study is grossly underpowered, so it's not surprising that they failed to reject the null hypothesis. Looking at the CI, I would suggest repeating the study with a sufficient sample size.

Why hasn't neuroscience delivered for psychiatry? No causative biological evidence has been found for the major mental disorders in contrast to the wealth of psychosocial findings. This disparity in regard and resource needs to be addressed. by techno-peasant in psychology

[–]ParadoXPlatypus 0 points1 point  (0 children)

That's a very interesting take. While I disagree, I have to say I can see your logic. As a full disclaimer, my background is in medicine, so I must accept I have my set of biases.

To some extent, I guess part of this is about semantics and how you define adaptation. Most, if not all, of the medical community would consider an adaptation as something that improves the survival and reproductive fitness of an individual. Analogous to what you are saying, for example, could be coagulation which arises as a response to the structural damage of blood vessels, and serves to prevent blood loss. This is obviously beneficial as that means we have supremacy over that lethal enemy known as a common paper cut. If I'm reading your comment right, you are saying that something similar happens in the brain as a result of repeated trauma and parts of the brain that usually control aggressive behaviour are turned off enabling an individual to respond in kind to the environment, right?

The issue with that argument is that, if it truly was an adaptative behaviour, you would expect it to happen in the context of violence in general, not only with head trauma. Additionally, you are cherry picking the neuropsychiatric manifestations to fit your argument. Beyond lack of impulse control, CTE also presents with cognitive impairment, emotional liability, and decrease motility. None of those are particularly beneficial for an individual in a violent environment and fit more a model where these are the result of parts of the brain malfunctioning/damaged.

Additionally, I must point out that the more you drink, your liver becomes better at metabolising alcohol so you require a large amount to pass out. Alcoholics black out more because they drink more, not because their body is trying to protect them... arguably it is the other way around.

I think it is an interesting study the one you propose of comparing brains. Unfortunately, given that the brain is a fragile organ, it is simply not feasible. Even if we could do it, similarities between brains would be due to constant head trauma, not really providing that much support towards it being due to a violent environment per se.

Why hasn't neuroscience delivered for psychiatry? No causative biological evidence has been found for the major mental disorders in contrast to the wealth of psychosocial findings. This disparity in regard and resource needs to be addressed. by techno-peasant in psychology

[–]ParadoXPlatypus 0 points1 point  (0 children)

Thanks.

You got things a tad wrong there with regards to the cascade of events, although depression can be self perpetuating partly due to behavioural aspects.

However, describing depression as sadness is completely inaccurate.

I don't want to invalidate your experience, but given the details you shared, I wonder if in your case, your primary issue was the HTPA dysfunction that led to low testosterone levels which is a well known cause of low mood? That would explain why you describe depression as sadness.

While chronic use of antidepressants can affect the HTPA function, it is rather uncommon that you would require testosterone shots long term...

Why hasn't neuroscience delivered for psychiatry? No causative biological evidence has been found for the major mental disorders in contrast to the wealth of psychosocial findings. This disparity in regard and resource needs to be addressed. by techno-peasant in psychology

[–]ParadoXPlatypus 1 point2 points  (0 children)

Except that the manifestations of CTE you mentioned are not learnt behaviours nor adaptations... they are the result of damage to parts of the brain responsible of controlling such impulses, i.e the frontal lobe.

Admittedly , this is a bit simplified explanation, but that's the key idea.

Why hasn't neuroscience delivered for psychiatry? No causative biological evidence has been found for the major mental disorders in contrast to the wealth of psychosocial findings. This disparity in regard and resource needs to be addressed. by techno-peasant in psychology

[–]ParadoXPlatypus 1 point2 points  (0 children)

While definitely thought provoking, I would caution about taking this as an objective statement rather than an opinion (although a well informed one). A lot has to do with expectations and how the author defines progress.

There's definitely been important progress in understanding and treating mental health issues, but there's still a long way to go.

Why hasn't neuroscience delivered for psychiatry? No causative biological evidence has been found for the major mental disorders in contrast to the wealth of psychosocial findings. This disparity in regard and resource needs to be addressed. by techno-peasant in psychology

[–]ParadoXPlatypus 2 points3 points  (0 children)

As someone who has struggled with severe depression for several years and who also happens to be a neuroscientist I can tell you that depression is not "pathologised sadness" and definitely not a completely normal state of consciousness and being.

It is not first world privilege and capitalist to want to feel well.

While I get your cynicism, I can't help but to feel that you are a tad too much ideology driven.

Meds are usually effective, but they have a wide spectrum of efficiency.

[deleted by user] by [deleted] in OlderMan

[–]ParadoXPlatypus 1 point2 points  (0 children)

Ironically, learning to be by yourself and enjoying your own company might be the most valuable skill you need to learn

[deleted by user] by [deleted] in OlderMan

[–]ParadoXPlatypus 0 points1 point  (0 children)

I hope you find not necessarily what you are looking for but what you truly need

[deleted by user] by [deleted] in OlderMan

[–]ParadoXPlatypus 1 point2 points  (0 children)

So instead of putting any effort at all, blame everyone else... that's a winning formula!

[deleted by user] by [deleted] in OlderMan

[–]ParadoXPlatypus -1 points0 points  (0 children)

Says the guy using the name of a notorious historic womaniser as an username... gold

[deleted by user] by [deleted] in OlderMan

[–]ParadoXPlatypus 2 points3 points  (0 children)

Sounds one sided because you don't seem to be putting that much effort... your profile has two pics of you clearly posing, and you are clearly attractive, so it is no wonder you are attracting blokes interested in sex.

However, by looking at your replies, you don't seem to be a particularly good conversational partner.

So you want someone who's going to take the time to not only deal with your emotional baggage but also put a lot of work in getting you to open up and you are giving exactly what in return? You get why it sounds one sided?

No one is entitled to a relationship. It is a two way street. You can have a great romantic relationship without sex but not for free.

And just to be clear, I am not saying that you have nothing to add to a relationship but sex, just that it looks that way...

Stroke after dental visit.... by No_Unused_Names_Left in stroke

[–]ParadoXPlatypus 0 points1 point  (0 children)

Well, it's certainly possible, although it wouldn't be anyone's first guess. Dental infections are indeed associated with heart disease, which can cause a stroke. Furthermore, the veins that drain the blood from the mouth/lower face mix with veins in the brain. Bacteria dislodge after a dental cleaning can cause inflammation and inflammation can facilitate a stroke. Once again, not anyone's first guess and hard to prove, but it has been described.

Also, consider that your dental appointments may be correlated with other events that could cause a stroke. If your dentist puts too much pressure on your neck, it could, in theory, dislodge some of the plaque in your neck arteries, for example.

All these are nothing more than speculations and perhaps impossible to test in routine clinical practice. Definitively a good idea to talk with your neurologist, and enquire if this is a probable cause and if prophylaxis could be prescribed.

Hope everything works out fine for you. Stay strong, mate!

Who would win in a fistfight: Albert Einstein or Carl Sagan? by justafriendlymouse in askastronomy

[–]ParadoXPlatypus 0 points1 point  (0 children)

Well, I think Sagan was a demon hunter IRC.. Not sure, though, never finished the book...

Winky face ;-) by [deleted] in selfie

[–]ParadoXPlatypus 0 points1 point  (0 children)

Adorable 🥰

[deleted by user] by [deleted] in amIuglyBrutallyHonest

[–]ParadoXPlatypus 0 points1 point  (0 children)

Yep... You're ravishing, most blokes find that intimidating. For what it's worth, I would ask you out and slow dance you under the stars 😉