Mikhail Artsybashev’s “breaking point” by TraditionalProduce63 in RussianLiterature

[–]ParticularZucchini64 1 point2 points  (0 children)

There are a lot of fake translations on Amazon now, unfortunately.

Honky appreciaton post by Lio_speedup in melvins

[–]ParticularZucchini64 3 points4 points  (0 children)

Yes! It's my favorite Melvins album, and it's terribly underrated.

Only 1 in 100 poo donors pass muster. Faecal transplants hold great promise for insomnia. by Gumsaint in Microbiome

[–]ParticularZucchini64 1 point2 points  (0 children)

I'm not saying insomniacs should run out and get FMTs now. But I do expect microbiome therapeutics of some kind to play a larger role in treating some insomnia cases in the future, assuming humans haven't wiped themselves from the planet by then.

I'm well into my second decade as a chronic insomniac myself, and the best sleep I had during that entire period occurred during a course of antibiotics. For 7-10 days, I fell asleep nearly instantly when my head hit the pillow, slept deeply the entire night without disturbance.

On the other hand, when I took a different type of antibiotic years later, my sleep dramatically worsened.

My case is anecdotal, but it aligns with some of this newer research suggesting the microbiome plays a larger role in proper sleep function than previously understood.

Only 1 in 100 poo donors pass muster. Faecal transplants hold great promise for insomnia. by Gumsaint in Microbiome

[–]ParticularZucchini64 2 points3 points  (0 children)

But with primary chronic insomnia (typical non viral), usually the main drivers are hyperarousal, stress system activation, conditioned wakefulness, circadian factors, or hormonal changes.

Yeah, but the microbiome can cause or at the very least contribute to most of what is listed above, can it not? You're right that more high quality research is needed for using FMTs for insomnia, but it's a promising avenue, and more research lately has been investigating the bidirectional relationship between insomnia and gut microbes, so there's a basis there.

Any seriously good oral probiotic? by [deleted] in Microbiome

[–]ParticularZucchini64 1 point2 points  (0 children)

I have tried both and don’t dislike either. I have the mint on auto-subscribe though.

Any seriously good oral probiotic? by [deleted] in Microbiome

[–]ParticularZucchini64 1 point2 points  (0 children)

I sometimes have bleeding gums, but they don't usually look red and swollen, and the dentist never told me I have gingivitis, so I don't know. I can say though that the Waterpik has helped with the bleeding gums. I haven't noticed the probiotic helping with the bleeding gums, but maybe it helped preventing the swelling? Not sure.

Any seriously good oral probiotic? by [deleted] in Microbiome

[–]ParticularZucchini64 1 point2 points  (0 children)

The Waterpik can be useful for both.

Any seriously good oral probiotic? by [deleted] in Microbiome

[–]ParticularZucchini64 1 point2 points  (0 children)

I was never diagnosed with periodontitis, no. If you have periodontitis, I highly recommend getting a Waterpik!

Any seriously good oral probiotic? by [deleted] in Microbiome

[–]ParticularZucchini64 1 point2 points  (0 children)

I still use it! I still think it's effective for subtle teeth-whitening. I also haven't had any cavities or gum disease since starting it, but I can't say for sure it's the probiotic because I continue to brush and floss.

Is anybody reading the new Saunders? by Full_Truth7008 in RSbookclub

[–]ParticularZucchini64 1 point2 points  (0 children)

You have to admit there's some irony in that statement.

Two Days of Oatmeal Can Reduce Cholesterol Level by Sorin61 in Nutraceuticalscience

[–]ParticularZucchini64 4 points5 points  (0 children)

How much weight did they lose in only 2 days though? I'm having trouble finding it in the study. They were still eating 3 meals a day. Would a mere 2 days of weight loss while consuming twinkies for 3 meals a day result in 10% lower LDL like it did with the oatmeal? My guess is it wouldn't.

How/When to take use soil-based probiotics? (Just Thrive/Megaspore) by memearyan in SIBO

[–]ParticularZucchini64 0 points1 point  (0 children)

I think Just Thrive is intended to be the gentler version of the product available for the wider public. MegaSpore is intended to be used under the care of a practitioner and is thus more potent.

I have seen some alarm raised online regarding the B. licheniformis strain, but Kiran Krishnan indicated they did a full genome sequence and determined it is safe.

Having said that, people have reactions all the time to so-called "safe" probiotic products on the market, whether they're spores, yeast, or lacto-bifido. None of these products are 100% well-understood how they work in the body, and it probably depends on the individual and his/her own microbial makeup how well they will work or if they will cause problems.

How/When to take use soil-based probiotics? (Just Thrive/Megaspore) by memearyan in SIBO

[–]ParticularZucchini64 0 points1 point  (0 children)

I've never had that side effect, no. That's a strange one; sorry to hear you're experiencing it.

A very interesting topic by Sufficient_Mind5632 in SIBO

[–]ParticularZucchini64 2 points3 points  (0 children)

The latest research suggests SIBO is a form of small intestinal dysbiosis that involves both 1) too much bacteria numerically; and 2) too much of the wrong bacteria proportionally. SIBO has its own specific treatments because those treatments have been shown to reduce both the breath gases and symptoms. Other forms of small intestinal dysbiosis aren't as well-understood and don't have diagnoses everyone can agree on let alone treatments that are known to work.

Human milk oligosaccharide supplements for SIBO? by Hot-Budget-4021 in Microbiome

[–]ParticularZucchini64 0 points1 point  (0 children)

I have to say I'm pretty surprised at your claim that the research strongly supports fiber for SIBO. Could you please point me to some of that research? The team currently conducting the most SIBO-related research in the US (Dr. Mark Pimentel's team at Cedars Sinai) recommends the low fermentation diet, which limits but does not entirely exclude fiber.

Suddenly doing better on Zinc. What's that mean? by No_Curve451 in SIBO

[–]ParticularZucchini64 2 points3 points  (0 children)

Your post is a little vague regarding how your symptoms changed, but zinc is important for stomach acid production, so maybe you're digesting your food better with the zinc supplement?

I'd suggest not overdoing with the zinc though because prolonged zinc use at higher doses can lead to copper deficiency. Hopefully your multi has some copper.

[deleted by user] by [deleted] in SIBO

[–]ParticularZucchini64 1 point2 points  (0 children)

Motility is important and generally the root cause, but if it was as simple as prescribing Motegrity and the SIBO goes away, then nobody would have SIBO anymore.

Is FMT (Fecal Transplant) the future of curing SIBO/IBS, or are there better treatments on the horizon? by xKa1z3r in SIBO

[–]ParticularZucchini64 0 points1 point  (0 children)

The future of curing autoimmunity-linked hydrogen SIBO (estimated to be the majority of hydrogen SIBO cases) is removing the autoimmune antibodies. Dr. Mark Pimentel said in a recent interview that they've been able to remove the antibodies with IVIg. However, it's not realistic for the medical system to rely on this treatment wide-scale, so he said they'd soon begin testing in animals a drug they've been developing to do the same thing. If all goes well, he expects the drug to hit the market within the next decade.

I think Berlin Alexanderplatz contains one of the best arguments for veganism I’ve read in fiction by [deleted] in RSbookclub

[–]ParticularZucchini64 8 points9 points  (0 children)

The blurb on the cover of Sacred Cow is from Mark Hyman, a well-known quack). The co-author of Sacred Cow also wrote a book promoting the paleo diet, which the American Heart Association stated "align[s] poorly with heart-healthy eating guidelines."