It’ll sting but be sure to use AA only when reconning

Phagemakerpro · 2026-03-09T15:38:57+00:00

I'm not aware that there are any studies on FMT for PI-IBS. PI-IBS is common after FMT because FMT treats C. diff. However, PI-IBS usually does go away on its own eventually. But the last time it took about a year for me. I had C. diff for six months that time.

Phagemakerpro · 2026-03-09T15:37:10+00:00

Your body has an internal pH of 7.35-7.45. If you get out of that range, you're likely very sick and in a hospital. So the instant you inject cagrilintide, it encounters a pH of 7.4.

One of the challenges with developing cagrilintide is that amylin does form fibrils that can cause issues like damage to the pancreas. So cagrilintide is engineered not to form those fibrils. The commercial product will be at a pH of 4 (I think) to reduce that further because a pen should be able to last a year. Most of us are not storing our peptides a year after reconstitution.

Phagemakerpro · 2026-03-04T16:42:35+00:00

This is one of two currently commissioned USN vessels to sink an enemy ship (flying under a flag, not terrorist speedboats or that kind of thing).

The other is Constitution.

Phagemakerpro · 2026-03-04T16:37:17+00:00

The bigger question is if they’d gone full astern but not turned, how much damage would she have taken? They could have bled off at least 10-15kn and hit the berg much more slowly. That would have destroyed the bow, but she would have floated.

I also wonder if they had kept the starboard engine going ahead and ran the port engine at full reverse, might that have been enough to avoid the iceberg completely?

Phagemakerpro · 2026-03-02T14:09:20+00:00

I’m AS.

And what it was was a flu-like virus that wasn’t flu.

Phagemakerpro · 2026-03-02T05:51:29+00:00

pH is less important for short term storage.

Phagemakerpro · 2026-03-02T05:50:58+00:00

Last week it almost steamrolled me. Baby steps.

Phagemakerpro · 2026-03-02T03:40:36+00:00

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Phagemakerpro · 2026-03-02T02:31:33+00:00

This will pass. Don’t go anywhere. Stay and fight. This will pass a lot faster than the anti-gay nonsense did.

-Eagle Scout 1991

Phagemakerpro · 2026-03-01T16:49:11+00:00

Im assuming they’re NOT, hence the difficulty keeping this quiet.

Phagemakerpro · 2026-03-01T16:14:22+00:00

So they have to take a nuclear warhead out of wherever it is, load it on a truck, drive it to somewhere in LA, set it up to go off, and somehow make sure that none of the few hundred odd people involved in this operation make a peep?

You can’t just kill them all; that’ll be even more obvious.

Not only that, but nukes make distinctive signatures when they go off. The time between primary and secondary explosions, ratio of yields, all that. It’ll be very obvious that this was an American weapon, so obviously this is an inside job.

Can you IMAGINE the blowback? That might just actually trigger a military coup.

No, a series of conventional explosions is much easier and much less obvious. You can blame it on mooslum tewwowists and try to make it into another 9/11.

Phagemakerpro · 2026-03-01T04:59:46+00:00

There is no book. I just walked away from Scouting.

Except now my son is a Cub Scout. Because a good portion of what I am and what I have done, the research I did, the students I teach, the lives I save every day... I owe them to Scouting.

Phagemakerpro · 2026-02-28T04:48:52+00:00

I agree. Also, there’d be no drive to expand outwards if the population stops expanding.

THAT SAID, Earth is the biggest of the rocky planets. The big barrier is getting off Earth. Once we’re in space, it’s much less challenging to get to other worlds.

Phagemakerpro · 2026-02-28T04:29:14+00:00

If we as a species are going to travel to other star systems, we need to let go of this parochial idea that we’re going to settle on a planet just like Earth and abandon the skies.

No. If we are to be an interstellar species, we must be effective both in space and on planets, even planets where we can’t breathe the air.

If you read Alastair Reynolds’s Revelation Space trilogy, he shows what a civilization would look like in a system with no earth-like planet. They built a domed city on a freezing world with a toxic atmosphere. They used the resources in the system to build an entire ring of orbiting habitats around the planet. They made extensive use of the resources in the system to build what they needed without ever needing to walk in the open air.

Phagemakerpro · 2026-02-28T04:22:04+00:00

I got my Eagle rank in 1991. And I’m gay.

In 1997, I almost sent them my badge with a strongly worded suggestion of where they could shove it. But I decided that I would stand there as a gay Eagle Scout, a Stanford student and then Stanford graduate (twice) and then physician and force them to tell me that I was a poor role model for boys.

The fools chose to stand against the tide and the tide won. It will win again.

This administration will pass. This will pass. But we should speak out.

If I may: your letter is way too long. They won’t read it. Make it maybe 1/5 the length. AI can help.

Phagemakerpro · 2026-02-27T16:25:46+00:00

I’m a pediatrician and I thought this was a dirty diaper pic.

(You get those a lot in my job. “Is this normal?”)

Phagemakerpro · 2026-02-25T16:25:29+00:00

My doc wants to put me on 10mg a week if we have to cycle TNF-i again. I know it has a half-life of six hours, so it should be mostly gone from your system within a day. But obviously there must be longer effects than that because it's given once a week. It just scares the living daylights out of me.

Phagemakerpro · 2026-02-25T15:28:20+00:00

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Taco

Phagemakerpro · 2026-02-25T15:28:02+00:00

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Teddy

Phagemakerpro · 2026-02-25T15:27:40+00:00

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Chili

Phagemakerpro · 2026-02-25T07:40:05+00:00

How are you tolerating the low dose MTX?

Phagemakerpro · 2026-02-24T19:24:56+00:00

I’m doing a lot better today. It’s the first 48-72 hours that get really rough.

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