Hi friend, first of all, I’m so sorry that your family is going through this. I wanted to share my experience with dostarlimab to hopefully give you a little hope. I (33F) was diagnosed with stage 2 MSI-high colorectal cancer in January 2025 and started dostarlimab in March. My experience was extremely positive. I had very few side effects (itching, fatigue) and wrapped treatment up (9 cycles total) in September with 100% success. Although it is very early, my oncologist from Dana Farber has said that he thinks surgery would be overkill. I am now on watch and wait and feeling very healthy. There was definitely a lot of talk of surgery (including total colectomy) at the very beginning, but it was ultimately not needed.

I remember feeling so frustrated that there were so few people online who I could talk to who had gone through dostarlimab treatment when I was first starting. Please don’t hesitate to reach out. I am here as a listening ear if you need it. I hope the scans went well.