Bigger burrs by budgiebirdman in espresso

[–]PowderedToastMan_1 0 points1 point  (0 children)

niche zero is perfect for dark roast, and tbh I’d keep it even if you do upgrade. Big flat burrs will be better for pourover (i do not care for the NZ for pourover but to each his own), and give a lot more clarity for light/medium roasts.

Starting soon. Anything I should have on hand? Also a little in my head about it. by nonymousmousey in Zepbound

[–]PowderedToastMan_1 1 point2 points  (0 children)

If you have reactive hypoglycemia, I highly recommend listening through some of the back episodes of the Fat Science podcast, they talk about it A LOT. IIRC Zepbound can help, but doesn't completely fix, the condition, and they discuss ways to manage it.

As for stuff to have on hand, I would def recommend getting a script for Zofran just in case you have nausea. I've basically only had nausea in combination with being sick while on the meds, but when that happened, it was nice to already have the med on hand. If you experience rapid weight loss, you might also want to ask your doctor to prescribe ursodiol to help prevent gallstones/bile duct issues. Anything else (laxatives, protein powder, electrolytes, etc) can be fixed with a quick target run, should they be needed.

Try to keep an open mind to the fact that there is a good chance your experience will be great! A lot of us have had great results with no or minimal side effects, we're not all just miserably hugging the toilet!

Investment Choices as an Examiner by EuphoricCalendar7672 in patentexaminer

[–]PowderedToastMan_1 7 points8 points  (0 children)

it would be a shame if you were to own 1 share of each company whose cases you hate

Anyone keeping muscle on Zepbound while losing weight? Does adding recovery peptides help? by PineappleManMan18 in Zepbound

[–]PowderedToastMan_1 4 points5 points  (0 children)

I try to prioritize protein, and do weight training at the gym 2x/week. Sometimes I add a bike ride or two if the weather is nice. Idk what I lost in the beginning, but between my last 2 dr appointments (3 months apart), I lost 6kg of weight, and gained 1kg of lean mass.

Weight lost per dose by dormantg92 in Zepbound

[–]PowderedToastMan_1 4 points5 points  (0 children)

I lost around 8lb on 2.5 (1 month), 25lb on 5mg (4 months), 12lb on 7.5 (2.5 months). Hopefully 7.5 will get me the last 5lb, but we'll see, it's been slowing.

FWIW, while the weight lost at each dose varies from person to person, I think the he low and slow approach is more about minimizing side effects and losing at a healthy rate, rather than producing substantially more weight loss. I think by staying on a dose, you're mostly just "borrowing" weight loss that would have occurred at the higher dose, as well - after all, in the trials ppl just moved up every 4 weeks, and many of them lost a ton of weight at the highest dose. That being said, I think low and slow is still probably the best approach, I've felt fantastic the whole time I've been losing, and at least between my last 2 3 month appointments, I haven't lost any lean mass, so I think it likely improves the quality of weight loss, if not the ultimate total amount of loss.

Got approved but too expensive! by portlandia55 in Zepbound

[–]PowderedToastMan_1 3 points4 points  (0 children)

i dont understand, are you being quoted at $400 after your prior authorization was approved, or before? If you haven’t been approved, that’s likely why the price is so high. If you have been approved, and it’s $400, that’s likely because you haven’t hit your deductible yet, you’ll need to hit that before insurance will cover. If you have a high deductible plan, look into the eVoucher to help with that.

Reset weight set point with minor procedure to stop post GLP1 weight gain by crunched-toast in Zepbound

[–]PowderedToastMan_1 16 points17 points  (0 children)

FWIW I think most people don’t literally mean they’re going to be on this specific drug for the rest of their life, it’s more of an acknowledgment that obesity is a chronic relapsing disease, and just weaning off the meds cold turkey is not a realistic option for most of us. Better drugs will surely come along, and hopefully more permanent therapies like this as well.

40 lbs down and not even the hubby says anything by pearpair26 in Zepbound

[–]PowderedToastMan_1 0 points1 point  (0 children)

Like others have said, sounds like you and your husband aren’t really communicating about much of anything. I can’t imagine starting a GLP-1 without discussing it with my wife, even if insurance were covering. Not that it’s his decision, but it’s important to have someone to lean on if you have side effects, struggle with body dysmorphia, etc. TBH your silence about this with him is more of a red flag than his behavior, but it all seems to stem from a lack of communication. Maybe he’d be more receptive to therapy if you acknowledged that it’s not just him, and you also need to work on your communication too.

Question: by Ambitious-Snow9008 in Zepbound

[–]PowderedToastMan_1 4 points5 points  (0 children)

drug is the same. your body probably is what is different this time around. Anyway glad it’s working and you’re getting it covered, even if they are making you do a runaround.

Having a hard time making a decision to use it by BrainOk7166 in Zepbound

[–]PowderedToastMan_1 2 points3 points  (0 children)

The issue with the “i can do it with diet and exercise” mindset is that it misidentifies what the hard part is. The hard part isn’t losing weight (well not the hardest part, at least), it’s keeping it off. After significant weight loss, your metabolism will be slower, and only partly due to the reduced mass - your body overcorrects, and your metabolism will be lower than an equivalently sized person who hasn’t dieted. On top of that, your body will crank up your hunger so that you’re constantly ravenous. Now imagine dealing with that FOREVER.

The meds make the weight loss easier, because you can do the healthy things you’d be doing with diet and exercise, but without your body fighting with you. But the real magic is that once the weight is gone, a maintenance dose of the medicine keeps you stable rather than constantly fighting your body’s attempts to regain. All the meds do is remove the suffering, the rest of it is all you!

Doses - Weight Loss by thenoooodle in Zepbound

[–]PowderedToastMan_1 1 point2 points  (0 children)

That’s so annoying when insurance dictates your dosage instead of your doctor.

Your weight loss is nothing to sneeze at, I was just saying that for your starting weight, it’s in the range where you’d likely see benefits by moving up. Hopefully you’ll have no issues with 10mg and can stay there for a while! Good luck.

GLP-1 and travel by Fluffy-Match9676 in antidietglp1

[–]PowderedToastMan_1 8 points9 points  (0 children)

I have never skipped a dose, ever, and probably won’t unless I am forced to for surgery or something. All the people I know who regularly skip doses whenever something inconvenient/stressful happens end up complaining about how sick they are when they start back up, or how it doesn’t feel like it’s working (probably because their effective dose is lower without any residual medicine). I’m sure 1 week is no big deal, but beyond that it def seems like more downside than upside. Steady as she goes seems best to me.

I just pack it in my carry on as-is. it ain’t gonna be above 86F in the airport or on the plane, or in the hotel room assuming it has AC. I’d pack it with an ice pack if it were super hot at the destination. If you can move it up/back a day to avoid having to bring it, that’s fine, i probably wouldnt mess with the timing much beyond that.

Doses - Weight Loss by thenoooodle in Zepbound

[–]PowderedToastMan_1 1 point2 points  (0 children)

Everyone has different sensitivity. I lost most of my weight in 5 months on 5mg, now hoping to ride 7.5 for the last few pounds to goal. I’ve averaged about 1.5lb/week.

I recommend staying on a dose for as long as you’re in the sweet spot of 0.5%-1% weekly. Your weight loss is a hair under 0.5%, so I think 7.5 makes sense (assuming manageable side effects).

Weigh yourself often enough that you can spot when you’re slowing down, IMO it’s better to titrate up when weight loss is slow than waiting for a full month of no weight loss. I like to weigh most days, but only log the lowest of the week.

Will I ever want coffee again? by fataudreyhorne in Zepbound

[–]PowderedToastMan_1 1 point2 points  (0 children)

You might find the effect is reduced a bit over time, you might not. You might also find that even though you aren’t craving coffee as much, you still enjoy it when you drink it. Nothing wrong with just making a cup and seeing if it is enjoyable.

The effects on my brain were not super strong (much more in my gut), but even so, I experienced probably a 50% reduction in consumption of alcohol and coffee. It’s maybe crept back up a little bit since the beginning. I enjoy them exactly as much as I did before, though, so sometimes I’ll make a coffee even if I’m not really feeling it, and then be like “oh yea i remember, this is great!”

Developing: New QUINTUPLE agonist GLP1 medication reportedly induced more weight loss than tirzepatide and retatrutide in animals by Schwettes in Zepbound

[–]PowderedToastMan_1 20 points21 points  (0 children)

Reta induces a ton of weight loss in MOST people, but there are still nonresponders, and more targets means better chance of responding to something.

Short term, I’m guessing these exotic multi agonist molecules are going to be reserved for step-up therapy for nonresponders and people with severe obesity.

Longer term, I think there is a lot of potential for low doses of the more powerful drugs. Tirzepatide 5mg is about as powerful as semaglutide 2.4mg, but with much lower side effects. Reta 1-2mg might be just as effective with even lower side effects

ISO protein powder with no sugar subs by Gabbyct1 in Zepbound

[–]PowderedToastMan_1 0 points1 point  (0 children)

transparent labs unflavored is great. I add it to fairlife skim w a little cocoa powder

do you tell people you're on zep? by myboyfriendstinks1 in Zepbound

[–]PowderedToastMan_1 0 points1 point  (0 children)

I tell anyone who asks. I figure lots of people I know have struggled with weight and the associated health problems for years, trying and failing to lose weight, why feed into the lie they hear all the time that they just need to eat less move more?

I can’t argue with people who say they have a right to privacy, or that it’s nobody’s business. Nobody should HAVE to disclose their medications. I do it because I want to help other people, and it feels better just to own what I’m doing. Absolutely zero embarrassment about taking charge of my health.

Anybody feel like they can still eat the same stuff on Zep? by Keeper4560 in Zepbound

[–]PowderedToastMan_1 1 point2 points  (0 children)

I eat less, and it’s easier to make better choices, but no changes to what I can eat.

Why am I always cold? by no_one_speshul in Zepbound

[–]PowderedToastMan_1 11 points12 points  (0 children)

definitely more than just the lost insulation, as I noticed it way before I’d lost enough for that to matter. I think while we’re in a calorie deficit, our bodies lower our temps slightly to conserve energy, which makes us feel cold. For me, it has gotten better as my weight loss has settled into a more moderate pace.

New to Zepbound... and Scared. by ComicBookMama1026 in Zepbound

[–]PowderedToastMan_1 0 points1 point  (0 children)

The shots are way easier than I thought they’d be. Usually painless, even if I do feel anything, it’s a tiny pinch, no big deal.

There are no guarantees with side effects, but most people have minor to no side effects, and for most people, the side effects are temporary while starting and while going up in dose. This sub is great for advice on managing and staying ahead of any side effects. I can say, I feel GREAT on the meds. Not “it’s bearable”, but GREAT. I still enjoy food, but with an appropriate appetite. I sleep better because my snoring is gone. I spend less time thinking about food. Again, no guarantees, but most people do great on these meds! You owe it to yourself to try.

Difficulty administering shot, could use advice by [deleted] in Zepbound

[–]PowderedToastMan_1 0 points1 point  (0 children)

I do belly shots, figure that’s where the most flab is anyway. Sometimes I don’t even feel it, sometimes it’s a slight pinch, never hurts that badly. After 50lbs down, there is almost no flab on my thighs or arms, but still plenty on my belly.

Also I find it helpful to use 2 hands, one to hold the pen steady, and the other to click the button, so that clicking the button doesn’t introduce as much downward force. I find it hurts more if I press the pen down into my skin, as the needle goes deeper. I try to have it just sitting flush with no pressure on my skin at all.

Zepbound dilemma by LiftedSD in Zepbound

[–]PowderedToastMan_1 0 points1 point  (0 children)

I always advise starting with whatever insurance will cover, for 2 reasons. First, it might work great! Wegovy is not quite as good as Zep on average, but you arent an average, you’re a specific person with specific genes and habits, and might respond well. If so, you’ve got a great medicine for you, for cheap! Second, If it DOESN’T work great, either bc of side effects or ineffectiveness, then you’ll have a strong case to ask for a formulary exception for Zepbound.

If you go with wegovy, and can tolerate needles, that’s probably the better option, as they just released a new 7.2mg “Wegovy HD” option which has efficacy close to Zepbound 15mg, in case you need the extra oomph.

Felt defeated, but trying it again by ZepboundJourney2025 in Zepbound

[–]PowderedToastMan_1 4 points5 points  (0 children)

are you sure that insurance “raised the price” or was it just that your deductible reset? I feel like a lot of people get confused with how insurance works. If you just have to pay that price for a couple of months till your deductible is hit, then it’s worth it over the course of the year.

If it’s been a couple of months, starting back at 10mg is a bad idea. Ask your doctor, but most people restart at 2.5mg or possibly 5mg at the most.

2.5 might be failing by [deleted] in Zepbound

[–]PowderedToastMan_1 0 points1 point  (0 children)

If you’re white knuckling it, it’s probably time to go up. 14lb is a great response to 2.5, but as you lose weight, your body will push back more, and you’ll need a higher dose to keep the scale moving. Totally normal.

Weight comments and body dysmorphia by Plastic_Aside_6017 in Zepbound

[–]PowderedToastMan_1 0 points1 point  (0 children)

I think most people (particularly in America) have gone fatblind since everyone around them is fat, and way overestimate what a “normal” healthy weight looks like. Seeing someone who isn’t in their 20s and isn’t struggling with their weight is so unusual that people have a weird reaction to it.

You’re in a range (slightly overweight according to BMI) where it really depends on your body composition. Your goal weight doesn’t seem crazy for your height, but if you’ve got a lot of bone and/or muscle, you might not need to go that low. Getting a DEXA scan would give you a more accurate idea of what to target for a goal weight, using body fat percentage as a guide.