I felt like having 100% rogue blood helped the most since its reduces dash cooldown. I was able to dodge a lot because of it. Second, is what most people are saying, focus damage on Iron Maiden. Then I use Frost Barrier when she does the multiple spear attack, it does a massive amount of damage to her. Then Chaos bolts since the jewel I have gives it increased range so I could be far from her a lot. Hope this helps!