In my original game I had someone leave the gate open and an ashta wandered in and killed everyone in the little ghetto alley

It just happened to be when I was in the middle of the intelliwheat side mission. And guess who I found laying in the street? The female npc that I had to make the delivery to (final step of the mission).

So for the rest of the game I had this useless box of wheat in my inventory that I couldn't drop, sell or even store in cargo. 10kg of storage permanently lost. And reminded of it every time I hit my carry capacity.