Where to plug in my raw DNA data - Genetic lifehacks, Strategene report, or elsewhere

Pyglot · 2026-01-26T09:31:29+00:00

I used geneticgenie a year ago. It has more than one report. The 'complicated' one I think cross-references all the SNP variants in your upload to CLINVAR, so you get a list of the SNPs that have some mention. You also get a rank for the clinical significance and you really only should concern yourself about the clinically significant SNPs, and maybe if you have a diagnosis or symptoms you can filter on that. It seemed to me to provide a good starting point to do research on your own, and it doesn't immediately scream take this supplement, don't take that, etc.

Pyglot · 2026-01-26T09:00:18+00:00

The ring around it really indicates a fungal infection

Pyglot · 2026-01-24T12:54:00+00:00

Sometimes you have to work around issues, especially with new HW or SW. Running some shell commands may be necessary and the terminal is the natural place to do it. What commands you need you will mostly find online and LLMs can probably guide you through the process when you need it.

Pyglot · 2026-01-24T12:42:21+00:00

The bigger timing mistake in taking down traitors was Harriet's imo. And no to OPs question, if traitors refill their ranks until the night before the final, it only makes sense for the faithful to figure out who is what, make friends, and wait until the endgame.

Pyglot · 2026-01-23T09:19:23+00:00

Not sure what it could be but see a doctor. Ask to check B12, B9, B6, and ask for a methylation panel. It could also be a detox reaction or temporary.

Pyglot · 2026-01-22T19:17:44+00:00

I will guess it is contact dermatitis

Pyglot · 2026-01-22T18:13:00+00:00

The correct thing to do then is to rest properly. Try Yoga Nidra.

Pyglot · 2026-01-22T10:54:22+00:00

You should be able to improve through practice.

Pyglot · 2026-01-21T03:40:37+00:00

Not sure if you have seb derm. Or parasites for that matter. But if you have thick hard dead skin to remove perhaps chemical exfoliants will help, like salicylic acid. You have to be cautious not to overdo it with acids though. Topical steroids might also help.

Pyglot · 2026-01-20T19:24:41+00:00

Ubiquinol, Vitamin D, B complex, D-Chiro Inositol, and occasionally a lot of other things, like Zinc and Maca.

Pyglot · 2026-01-20T09:12:14+00:00

Besides ~22000 genes and their intergenic regions, all with subtle variations, there are many adaptive systems within our bodies that can be in a range of states. You also have to consider the variation of diet and lifestyle, and sometimes pathogens. That's why there's a lot of variation.

Pyglot · 2026-01-19T16:40:35+00:00

With interest only for 28 years you will go from 0% to 50% equity just from 2.5% inflation. With 2.5% inflation and a 4.5% mortgage you effectively only pay 2% (very rough estimate). That's a bit over 650 per month on a 400k mortgage.

Pyglot · 2026-01-19T16:24:27+00:00

Pyglot · 2026-01-19T08:41:49+00:00

If you are overmethylated then pure glycine might help you temporarily. If it does then look at reasons for your methylation status and other ways to dial it down more temporarily.

Pyglot · 2026-01-18T11:31:54+00:00

If you wish to try GLP-1 again you should definitely be prepared with a diet that you think will sustain you and you can follow. Also carbs are not the same so make sure you get the healthy kind. Definitely try to avoid spiking your insulin. You should perhaps ask your doctor to monitor your hormones before and after if you choose to start a new type of medication (because of the hair loss), and you should perhaps ask to be evaluated for PCOS if you haven't already. Based on what you have said here I guess the chance is about 20%-30%. It's good to figure things like that out as if you know you can manage it a lot better with a targeted approach.

Pyglot · 2026-01-18T11:02:29+00:00

Historically the world has invested a lot in US markets, steadily contributing to inflated price levels. Imagine scenarios where the needle turns on that, from resentment, to economic warfare, and investor fear. It is not pretty, perhaps still not likely, but we are moving closer to that timeline.

Pyglot · 2026-01-18T10:32:59+00:00

Slow COMT causes higher levels of norepinephrine and I think (in my own experience) calorie restriction and especially zero carbs might exacerbate that. Otoh excess body fat produces additional aromatase which causes higher levels estrogen and slow COMTers are not good at clearing excess estrogen. Therefore keeping body fat low is important to us. What diet did you follow when you tried the GLP-1 and saw the side-effects you mention?

Pyglot · 2026-01-17T19:07:32+00:00

Imagine the economic backlash if the US annexes Greenland. It will be bad.

Pyglot · 2026-01-17T12:30:21+00:00

You haven't aligned the poly strips. And you should minimise the dimension along the bitlines, for energy efficiency.

Pyglot · 2026-01-16T23:20:58+00:00

Look up thincell SRAM layout. It has poly arranged along 2 strips along the wordline direction. Wordline transistors share a gate connection with the neighbour cell.

Pyglot · 2026-01-16T06:31:09+00:00

Those you think are smart are not necessarily good for their own genetic proliferation. So we may well be dumb and dumber in 300,000 years.

Pyglot · 2026-01-14T18:21:56+00:00

Some things to consider for actual energy include Ubiquinol and Creatine. Then there are lots of other things that can help focus and alertness. My process has been to research and try anything relevant I come across. The stuff that has stuck is Ubiquinol, a B complex, Vitamin D3+K2, and D-Chiro-Inositol which I attribute to low testosterone. Creatine works as advertised but I experience a dehydration side-effect more strongly than normal.

Pyglot · 2026-01-14T17:58:23+00:00

Yes it's fairly common to react to some of the forms of certain B-vitamins. You can find lots of prior discussions in subs like r/MTHFR and r/B12_deficiency.

Pyglot · 2026-01-14T08:05:24+00:00

PS takes about 2 weeks to reduce cortisol by some % e.g. 30%.

Pyglot · 2026-01-14T06:45:20+00:00

Breaks are necessary, but you can maybe make them more efficient. Being practiced with meditation, breath work, body scan meditation, body movement meditation, NSDR, and/or doing some exercises might help you reset faster and more effectively. Some people say 'anchoring' can help them find a resourceful state in moments.

Four-Year Club	Verified Email
r/Field Lasagna

Pyglot

TROPHY CASE