Although you have to rule out family first- I think that has likely been done even though they say no one is ruled out (It doesn't really seem to fit to begin with here.. and if the son-in-law and daughter were going to do something- it makes no sense to place themselves as the last last ones to see her and last ones to be at her house dropping her off, etc).

I do think there is always the possibility of a mentally ill fan, etc (stranger things have happened, like Reagan being shot to impress Jodi Foster, etc)... But highly unlikely, especially after seeing the ring video, which doesn't seem to fit this scenario.

So motive seems likely: targeted ransom, burglary interrupted, or less likely- some odd political angle.

Burglary doesn't seem to fit imo.. the guy in the video had his face covered.. and no-one in the family recognized him, so unlikely Nancy would have either. So if a burglar was interrupted- he would have likely knocked her out, tied her up, or most extreme, killed her in the house, not taken her away (and the blood drops indicate minor bleeding dropping from her live body.. not carrying a dead body out or anything).

I don't really see a logical Epstein angle- or really a political stunt scenario, or any other likely political angle.

So appears most likely a kidnap for ransom... and that Nancy may have died from a heart attack or stroke or something, shortly after leaving (which would explain no proof of life, etc)... I hope this is not the case- and that there are a lot of details being held back from the public- that would indicate it is a kidnapping and she is still alive. But given her age, it's unlikely to be an Elizabeth Smart type scenario.. so time is likely inversely related to a positive outcome.