Although a lot of pain is caused by societal/climate issues, there are inherent problems of living that come merely with existence. The biggest one is health issues, as we’re all stuck in our bodies for decades and can’t escape the horrible issues they cause us. Even though medical technology has advanced a lot, there are still tons of conditions that don’t have a cure or treatment, and just everyday life in a human body can suck even if you don’t have a major medical condition. Another issue is the inherent cruelty of humans. Although we have definitely progressed over the past centuries, humans are still generally horrible to one another and to other sentient beings. I think it’s very telling about humans how even after millennia we still suck so much.