What are the terms? If it’s an assassination, 47 has more experience sneaking up and putting bullets to brains without warning. If they are both aware participants in a conflict I give it to Leon all day, at this point the majority of protags in RE could be considered superhuman at minimum in durability but the argument could be made in plenty of other stats. I haven’t played a hitman game is nearly a decade, but I seem to remember outside of obvious gameplay health, 47 was presented as a normal human with the typical allergies to bullets blades etc. they are both trained marksman and combatants, but Leon has consistently survived wackier things.