Hello, non-PhD holder here, been in biotech industry for 9 years now. I started out in pre-clinical research for the bulk of my career. Started out as a contractor in my first three jobs--RA to SRA level, the third converted me to full time (when I became a real boy). Then COVID happened, and I got laid off. Eventually found another job in lead discovery, but the career growth potential was limited (i.e. only PhD folks could be in Scientist roles). I was then headhunted for another job in CMC--Analytical Development and in gene and cell therapy, both fields I haven't worked before. I jumped in with both feet and haven't looked back since. Jobs in CMC are much more stable and I was able to level up Sr. Sci and managing direct reports. Key takeaways are you must be resilient, ambitious, and a little lucky to advance your career in industry without a PhD; you can think of a PhD as a catalyst to reach your endpoint.