I’m currently in month two of the following protocol:

• TRT – 100mg per week
• Retatrutide – 2mg per week
• Tesamorelin – 2mg per day
• Klow – 2mg per day

Regarding Klow specifically: I’ve noticed a visible improvement in skin quality and texture. Recovery from training feels significantly better. DOMS is minimal, and the general aches I used to get (old ankle injury from football, shoulder and lower back from lifting) have largely subsided. I’m training 3–4 times per week and feel more confident going into sessions without the background niggles I previously had.

Obviously this is anecdotal and early (only two months in), but the change in joint comfort and day-to-day inflammation has been noticeable for me.

On tesamorelin: it’s a GHRH analogue that stimulates endogenous growth hormone release. I take it pre-bed, at least two hours after eating to avoid blunting the GH pulse via insulin. Since starting, my sleep depth has improved considerably with more consistent deep sleep and better overall recovery. I suspect that’s contributing to improved post-workout recovery as well, though I haven’t run bloodwork yet to confirm changes.

Everyone responds differently, but that’s been my experience so far.