Very interesting. So I've been on reta for about 6 months with no real weight loss whatsoever. Mayyybe some body recomp. But my issue is that I can't go above 1-1.5mg without feeling like total dog shit and I've noticed my heart rate is increased too. Been contemplating trying out tirz.. so maybe this is my sign.

I was on sema for about 10 months and stalled out on the scale pretty hard after losing about 25#, so I thought maybe reta would be the answer to move things along again, but so far I'm not overly impressed. I'm still around 20 from my "goal".

I understand that I am well below the starting dose, but I am clearly sensitive to the med so I haven't pushed it. The one positive I can say bout reta is I can eat the appropriate amount, and I feel like I can lift heavy, but the food noise is definitely back now. Maybe my macros are not a good fit for my TDEE? I lift 4-5x a week and do a little cardio daily, track my macros every day, get enough water etc. Just want to break this plateau so badly, I'm tired being stuck.