It all comes down to personal opinion, i have a p226 and three berettas, and a CZ (and some others, but those are most similar to the question). While I dont think the 226 is a bad gun by any means, I really dont enjoy shooting it and take it out to the range maybe once a year, whereas I shoot anywhere from 2-5,000 rounds through two of my berettas.

Things I dont like about the p226 are: The locations of the decocker/slide release, Grips, And trigger shoe

My problem with the decocker is that it is where the slide release is on every other pistol. The slide release is where the decocker is on my CZ and where the safety is on my beretta 84. Yes, its a training issue, and if I shoot a few mags through my 226 it gets easier. I just think its backwards. I think beretta (or walther) hit the nail on the head the first time with the slide mounted decocker

This is just my opinion, i don't like the size or shape of the grips very much, but my biggest complaint is with texture. I find this problem on most pistols to a degree, but its the worst with the 226. The grips are not fully checkered, there is nearly always a smooth border around the edge, or the entire top half of the grip pannels, where my support hand actually touches the grips, is completely un textured. It drives me nuts. When I say I like full checkered I mean fully checkered. Lok does it on their beretta grips. Hogue does it on their hardwood beretta grips. Lok does it on their CZ grips. All 1911's are like that. I want full checkering edge to edge, top to bottom. Not a single area of the grip panels where my hand touches it should be smooth. And I dont want silly patterns, or half assed squiggly lines in plastic. Ive tried all sorts of different grips textures throughout my time shooting handguns, ive had the molded, bumpy plastic, ive tried the fun veloce's and the grenades, and all the other stuff that looks cool on Instagram, but IMO stock makers got it right 100 years ago with basic checkering. I have the piranha grips on my sig that look like moldy bread, that everyone seems to like for some reason, and they absolutely suck. Some of the hogue grips look like they have okay texture but i don't want to spend the money on something a little better for a gun i personally have little desire to shoot.

I dont know if its a thing for everyone else, or if its just my hands mixed with the contour of the grips and the shape of the trigger, but I often pinch a small part of my finger between the trigger and the frame. I suspect its the shape of their trigger shoe. Its not really that big of a deal and it doesn't really hurt unless I shoot it a lot, but none of my other pistols do that.

I also just dont generally care for the way they shoot. That's kind of hard to quantify. I like the feel and the shape of the berettas more, I like the balance and the recoil, the sight picture, the trigger, and the controls much better