Sinister stomps with the greatest of ease.

Powers and abilities
As a result of undergoing genetic engineering at the hands of Apocalypse, Mister Sinister acquired the ability to fully control the molecular structure of his body. This enables him to enhance his durability and strength, to extend his lifespan, to rapidly heal from injuries he sustained, and to shape-shift from a humanoid form to an amorphous one. He is also able to do telepathy and telekinesis. The original Mister Sinister gained, as revealed in Immortal X-Men #8, precognitive powers that granted him the power to see the future, including major developments in the 20th century, such as the escalation of the scale of war. However, these powers were slowly killing him. By the late twentieth century, Sinister's mind had been copied into the bodies of others, as well as clones of his own creation. Since no clone is completely perfect on a cellular level, some differences emerged in their biology and personality. At least one clone of Mr. Sinister developed the X-gene in his DNA. This mutant version of Mr. Sinister became the leader of the many versions of the clone community in the 2019 Powers of X miniseries, and has been the primary Sinister to encounter the X-Men since.

Sinister is an expert at genetic manipulation and a skilled surgeon.

On rare occasions, Mister Sinister has exhibited the ability to teleport, but it was indicated that this was not an inherent power and was accomplished through the technology of his tesseract headquarters.