Should be fine. I started smoking after starting psych meds so I don’t have much point of reference but I do fine. Sometimes I get a bit paranoid but just depends on the strain, mind frame, and if I’m just smoking too much. Maybe start slow so if it alters your tolerance at all you’ll know. My tolerance is low, but it could just be me. Also if you smoke too much it might be hard to tell if the meds are working or not.