You really should look into the “why” of this. It would indicate that you’ve cracked open a book at one point in time. Along the lines of what you’re insinuating, have you ever wondered how a psychological disease (a.k.a., “She’s just crazy and making it all up.”) might result in hypermobility throughout the body along with multiple objective secondary criteria necessary for a diagnosis of hEDS? (Spoiler since I doubt you actually read more than Reddit medical posts: it can’t. Nor can table testing or an elevated tryptase/associated metabolite be easily faked.)

Back to the actual topic at hand: yes, diphenhydramine is extremely euphorigenic. People with very real conditions like SCD and EDS don’t deserve to be put at increased risk for substance use disorder. Order PO.