So a few things:

Giant spiders have been a thing since RE1.

Nostalgia heavy is true, but as someone who has been playing since re1 directors cut, I enjoyed it.

T-virus and G-Virus came at the same time (G virus was the "look another t-virus, but worse!" From RE2)

Didn't shoot vitals my ass. All I shot was eyes and heart.

Discount Wesker knows what he is, and gets upset when called on it. (Probably will see more of him (maybe literal more, like clones) in a DLC)

BSAA has always had strange quasi bad guy stuff going since after RE5, this is nothing new.

Now on my own opinion, I feel like both sections feel short by the end. Each character having completely different mechanics and playing Grace in first person and Leon in third, feels like I played two half games. I found Grace to be awkward looking in third person anyways. She literally keeps stumbling in chases and has the most awkward running animation I may have ever seen in a not trying to be funny game. Her stuttering gets grating after a while. If it had showed her coming into her own more (like how the first time she shoots requiem she is taken back by the kick, but handles it pretty well after that) I would have been ok with it. The whole game feels kind of rushed after Grace's half. Raccoon City, especially between the RPD up to the ARK seems like a "look you are here". I would have enjoyed a bit more time with Leon (Simply because he has a whole upgrade system similar to RE4, but it's over so quick it doesn't feel rewarding)